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Cyclosporine A and pterygium fibroblasts

The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...

Leading sight loss charity reveals urgent need for change in attitudes towards blind mothers

Ahead of Mothers’ Day, leading sight loss charity the Royal National Institute of Blind People (RNIB) has released research that shows the barriers faced by mothers with sight loss during pregnancy and into their first years of motherhood. This research...

Problems in Periorbital Surgery: A Repair Manual

This is a multi-author textbook directed at oculoplastic and plastic surgeons carrying out and managing aesthetic eyelid surgery. The authors are well-known and commonly cite their mentor, Clinton (“Sonny”) McCord as the main inspiration behind the textbook. Each section contains...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Glasgow-based eye surgeon, Dr Tim Lavy, speaks into new vision and new life for Mamadou

The moment a seven-year-old boy sees clearly for the first time has been captured in a video by the charity that gave him free surgery. Surgeons from international charity Mercy Ships believe Mamadou, who lives in Sierra Leone, would have...

Santorini sunlight!

In the heart of London, Hollywood icon Keanu Reeves attended his inspiring book launch event held at the Royal Festival Hall, later followed by a book signing at Waterstones in Piccadilly, London. Ticket holders included ladies from the Literacy Ladies...

Trabeculectomy for normal tension glaucoma

This is a retrospective consecutive, non-comparative case series of 131 eyes of 98 patients undergoing trabeculectomy between 2007 and 2013 in a normal tension glaucoma (NTG) clinic. Assessment of the clinical outcomes include intraocular pressures (IOP) reduction, bleb formation, final...

A guide to the Multi-Speciality Recruitment Assessment (MSRA) exam

The MSRA exam is a mandatory part of the application for ophthalmology specialist training in the UK. It is a computer-based exam which is designed to assess junior doctors with foundation level competence. It is used for entry to postgraduate...

Semaglutide and vision loss: A new concern for NAION risk?

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as transformative agents in...

The choroid in pregnancy

During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...

Diagnosis and management of IV cranial nerve palsy

Aetiology: Trochlear nerve palsy can be divided into acute or congenital. Congenital trochlear nerve palsy is usually noted in childhood with development of abnormal head posture. Various pathologies can lead to acute IV nerve palsy, most commonly trauma. Other causes...

A case of retinal cavernous haemangioma – don’t let it slip through the grapevine

We present a case of a seven-year-old male who presented to the emergency eye referral clinic with red eye. He was diagnosed and treated for allergic conjunctivitis, however, on clinic review, wide field retinal imaging was performed (as has been...