You searched for "macular"

2432 results found

25 years of OCT

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection

In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...

A Case-Based Guide to Eye Pain: Perspectives from Ophthalmology and Neurology

A refreshing, systematic approach to eye pain, arguably one of the most commonly presenting symptoms and one that can be fraught with diagnostic challenges and management dilemmas for the busy clinician. There is a scarcity of books covering this particular...

Paediatric optic disc anomalies

Anomalies of the optic nerve are relatively rare, but account for a significant proportion of sight impairment in children and adults. The recognition of these anomalies by eye health professionals is important not only due to their potential impact on...

The choroid in pregnancy

During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...

How many injections in nAMD: ranibizumab vs. aflibercept

Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...

Vitrectomy after ocriplasmin for VVMT adhesion of MH study

This is a multicentre retrospective study of 51 eyes that received intravitreal ocriplasmin between January 2013 to January 2014 for symptomatic vitreomacular (VMT) +/- macular hole (MH), and then went on to PPV for persistent pathology, comparing a control group...

Detection of antiranibizumab antibodies in exudative AMD

In this study the authors aimed to detect immune response to ranibizumab treatment in wet age-related macular degeneration (AMD). An ELISA was employed to quantify the anti-ranibizumab titre which was compared against the control anti-abciximab titre. Titres of anti-ranibizumab antibodies...

Visual acuity after cataract surgery in AMD patients

The data from this study are obtained from the Age-Related Eye Disease Study (AREDS) 2 and analysed to evaluate if cataract surgery benefits patients with concurrent age-related macular degeneration (AMD). The AREDS 2 was a five year, prospective, multi-centre randomised...

The long-term effects of AREDS on AMD progression

The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Radiation maculopathy

This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...

Risk of CNV related to angioid streaks in PXE

This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...