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Topical atorvastatin for dry eye and blepharitis

Dry eye is a very common problem with 20% of the population affected and is frequently associated with blepharitis (DEB), which has an over prevalence of about 40%. The aim of this study was to evaluate a topical atorvastatin formulation...

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease

Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....

How to nearly (but not quite) get into ST1 ophthalmology training – some reflections

Ophthalmology is often considered to be an elite, highly competitive specialty, with little room for failure. Candidates and trainees tend to cultivate a certain urbane and confident style, and the bottleneck at ST1 can feel rather intense. The majority of...

Foundation Post in Ophthalmology

If you are in your final year of medicine at university, firstly congratulations on making it so far and secondly, you may be wondering how and which jobs to rank highly. If you have found yourself reading this article, then...

UKISOP and the allied health professions

In ophthalmology practice today there is a vast number of training and educational opportunities for staff from all professional backgrounds. The key is to use your study leave and funding wisely! In the first of this series of articles, signalling...

Diabetic Retinopathy Network laser training programme

The VISION 2020 Diabetic Retinopathy Network (DR-NET) was established in 2014 to tackle the increasing burden of diabetes and diabetic retinopathy (DR) in developing countries [1]. By forming a network of long-term LINK capacity-building partnerships, learning and best practice can...

Gemini Untwined: treating craniopagus conjoined twins

The authors discuss the successful separation of craniopagus conjoined twins at Great Ormond Street Hospital and the role of the ophthalmologist in such cases. Craniopagus conjoined twins are extraordinarily rare, occurring in only one in 2.5 million births and representing...

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy

Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy, offering new ways for future therapies to target this common, age-related cause of visual loss. In a landmark study, researchers supported by NIHR Moorfields Biomedical Research Centre, have identified...

Effective management of dry eye and ocular surface disease

Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

What's trending Feb/Mar 2024

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ScleralTattoo #BlackEye Scleral tattoos aren’t necessarily a new phenomenon. A quick google search will identify cases being in the news from...

MicroRNA mediate retinoblastoma signal transduction

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...