You searched for "neuropathy"
Review of non-arteritic anterior ischaemic optic neuropathy
1 October 2016
| Chrysostomos D Dimitriou
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EYE - Neuro-ophthalmology
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Neuroprotection, optic nerve ischemia, optic nerve vasculature, primate models, rodent models
This article reviews the risk factors, clinical presentation and therapies that have been investigated for non-arteritic anterior ischaemic optic neuropathy (NAAION). Additionally, it provides an update from recent rodent and primate models, offering a new insight into the pathophysiology of...
Case report of Leber hereditary optic neuropathy (LHON)
1 October 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Central scotoma, Leberhereditary optic neuropathy, macular hole
This case report presents a 74-year-old male patient who developed LHON, with a previous diagnosis of bilateral macular holes. LHON occurs predominantly in healthy young men and onset in older age ranges increases the likelihood that the patient will have...
Anterior ischaemic optic neuropathy post cataract surgery
7 April 2021
| Tasmin Berman
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EYE - Neuro-ophthalmology
This retrospective population-based cohort study assessed whether there was an increased incidence of anterior ischaemic optic neuropathy (AION) post cataract surgery compared to patients that had not had cataract surgery. They reviewed the notes of all patients diagnosed with AION...
Comparison of central laminar thickness in optic neuropathy and normal eyes
The study compares central laminar thickness (LT) among patients with glaucomatous optic neuropathy (GON), patients with non-GON and normal subjects. The non-GON group comprised eyes with demyelinating optic neuropathy (ON), anterior ischaemic ON, compressive ON, Leber hereditary ON and traumatic...Positive diagnosis of acute posterior ischaemic optic nerve neuropathy
1 December 2015
| Claire Howard
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EYE - Neuro-ophthalmology
Posterior ischaemic optic neuropathy is a rare cause of visual loss believed to be due to infarction in the territory of the pial branches of the ophthalmic artery. There is an absence of clinical signs which means the diagnosis is...
Non-arteritic anterior ischaemic optic neuropathy (NA-AION): a review
1 February 2017
| James F (Barry) Cullen
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EYE - Neuro-ophthalmology
Ischaemic optic neuropathy (ION) is the commonest adult optic neuropathy encountered today in our ageing population, is a common cause of irreversible visual loss and is usually associated with underlying vascular disease. The condition is classified as follows: (a) Anterior...
Risk factors for non-arteritic ischaemic optic neuropathy in an Asian population
1 October 2017
| Claire Howard
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EYE - Neuro-ophthalmology
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Korean, non-arteritic anterior ischaemic optic neuropathy, systemic risk factor
The authors reviewed the medical records of 45 Korean patients with non-arteritic anterior ischaemic optic neuropathy (NAION) and 45 healthy controls, in order to determine risk factors for the condition in an Asian population. Previous studies looking at risk factors...
Choroidal and macular thickness in nonarteritic anterior ischaemic optic neuropathy
1 December 2014
| Claire Howard
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EYE - Neuro-ophthalmology
This study evaluates the choroidal and macular thickness in patients with chronic nonarteritic anterior ischaemic optic neuropathy (NA-AION). Two groups of subjects were compared, group one included 20 eyes with chronic NA-AION and group two, 31 healthy control eyes. The...
Investigation of blood platelet parameters in anterior ischaemic optic neuropathy
1 August 2019
| Claire Howard
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EYE - Neuro-ophthalmology
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Anterior ischemic optic neuropathy, mean platelet volume, neutrophil to lymphocyte ratio, platelet distribution width, plateletcrit
The aim of this clinical retrospective comparative study was to assess the possible relationship between arteritic anterior ischaemic optic neuropathy (AAION) and non-arteritic anterior ischaemic optic neuropathy (NAION) with blood platelet parameters and neutrophil-to-lymphocyte ratio (NLR). The medical records of...
Non-arteritic anterior ischaemic optic neuropathy in the Asian population
1 October 2014
| Claire Howard
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EYE - Neuro-ophthalmology
This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...
Visual prognosis in Irish Leber’s hereditary optic neuropathy
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Leber’s hereditary optic neuropathy, idebenone, inherited optic neuropathy, mtDNA, ophthalmic genetics, optic atrophy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...
A novel way to distinguish between types of anterior ischaemic optic neuropathy
7 April 2021
| Claire Howard
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EYE - Neuro-ophthalmology
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Anterior ischaemic optic neuropathy, inflammation, monocyte to high-density lipoprotein ratio
The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...