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Boston type I keratoprosthesis for limbal stem cell deficiency
Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...
AlloDerm for correction of lower lid retraction
This is a retrospective review of 95 eyes of 54 patients undergoing orbital decompression for Graves’ orbitopathy. All patients had a swinging eyelid approach across the whole of the lower lid. Thirty-six eyes also had insertion of a 0.3mm thick...
Natural regression of brow heaviness in thyroid eye disease
This is a retrospective review of the change over time in the sub-brow fat volume in 104 patients with thyroid eye disease. Standardised photographs taken at diagnosis were compared with those taken after an average period of 10 years (+/-...
Platelet-rich fibrin for conjunctivoplasty after pterygium excision
The authors report a prospective, comparative, non-randomized clinical trial of 35 pterygium patients with unilateral nasal primary pterygium infiltrating the cornea 2-5mm in size, who underwent pterygium excision between June 2013 and September 2014. Thirty-five eyes of 35 patients with...
IAC vs. IVC chemotherapy for RB
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
Systemic pharmacology of intravitreal anti-VEGF
This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...
Aqueous humour cytokine levels in PCV and nAMD
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Intravitreal dexamethasone implant for diabetic macular oedema
The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...
Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification
This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...
Moxifloxacin 0.5% for bacterial keratitis
The authors report on the results of a randomised controlled trial comparing commercially available non-preserved moxifloxacin 0.5% vs. a combination of fortified cefazolin 5% and tobramycin 1.3% in the treatment of moderate bacterial keratitis without perforation. Corneal scrapings were collected...
Long-term results of cross-linking treatment for keratoconus
The authors report on the long-term outcomes in a prospective case series of patients with keratoconus undergoing corneal collagen cross-linking (CXL) treatment. Thirty-two patients (40 eyes; mean age 22.5+/-5.5 years) with Grade I, II and III progressive keratoconus were recruited...
