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Shedding light on Wolfram syndrome: The unveiling of a delayed diagnosis

12 August 2025 | | EYE - Neuro-ophthalmology
Wolfram syndrome 1 (WS1) was first described by Wolfram and Wagener in 1938 and it’s a rare neurodegenerative, progressive disorder, also known as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) [1]. We present an atypical case of WS...

A closed angle seldom comes alone

1 June 2017 | | EYE - Glaucoma
Case report An 89-year-old lady with dementia was referred to me out of hours by her GP with a few days history of an angry looking left eye for suspected elevated intraocular pressure (IOP). I discovered that this lady first...

Papilloedema: an update

1 June 2016 | | EYE - Neuro-ophthalmology
Some readers may have seen a recent report in the national newspapers of the case of a teenage girl with persistent severe headache associated with a fatal brain tumour having been undiagnosed despite many consultations with her medical advisers. It...

What to expect when meeting a statistician

1 August 2014 | | EYE - General
There are a growing number of statisticians working closely with ophthalmologists. They have different training but they are driven by the same goal: to perform high quality evidence based clinical research [1,2]. In a perfect world we would simply conduct...

What’s Eating Gilbert Pete

2 August 2022 | | EYE - General
“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

How to maximise points for your ophthalmology portfolio as a medical student

4 December 2023 | | EYE - General
Ophthalmology is an extremely popular and competitive career option, with one of the highest competition ratios at ST1 level entry (10:1 in 2023) [1]. It is also a highly rewarding speciality, involving: a mixture of medicine and surgery in a...

A Nightmare on Doctor Street: Two

4 October 2023 | | EYE - General
Just when you thought it was safe to go back into the clinic room… The quote below comes from Rudy Baylor, a graduate fresh out of law school and recruited by a ruthless ambulance chaser in the legal drama movie,...

Can 3D facial imaging improve patient management in disfiguring eye disease?

1 August 2015 | | EYE - Imaging, EYE - Oculoplastic
Fight for Sight is the leading UK charity funder of eye research. Since the 2013 Sight Loss and Vision Priority Setting Partnership we have encouraged our researchers to work on priorities jointly identified by people affected by sight loss and...

NYU Langone Health performs world’s first whole-eye & partial-face transplant

15 November 2023 | NYU Langone, eye transplant, Face transplant, surgery, therapies, Aaron James, USA, Eduardo D. Rodriguez
Landmark whole-eye transplant is a major paradigm shift for potential vision therapies.

My ophthalmology elective: East to West

7 May 2026 | | EYE - General
I was fortunate to be able to complete my elective in three different parts of the world: the UK, Vietnam and Pakistan. I spent three weeks at Bristol Eye Hospital (BEH), two weeks at Cho Ray Hospital in Ho Chi...

Serendipity

3 October 2024 |
“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...

What not to miss in neuro-ophthalmology Part 1

1 April 2018 | EYE - Neuro-ophthalmology
Neuro-ophthalmology is a complex and difficult subspecialty in ophthalmology. It has several connections to neurology, neuro-surgery, rheumatology as well as many other medical specialties. Working in an multidisciplinary team (MDT) environment is key to success in this subspecialty as mistakes...