You searched for "innovation"
A personal reflection: working at the International Centre for Eye Health from 2006–2024
I feel incredibly fortunate to have been working part-time at the International Centre for Eye Health (ICEH) [1] since 2006. Earlier in my career, the responsibilities of work and a growing family made this merely an aspiration, and apart from...What’s trending? Oct/Nov 2017
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #NHSwaitingtimes, #NHSprivatisation, #NHSpostcodelottery The NHS in crisis seems ever topical, but this time, the focus is on long waiting times...Refractionist’s shoulder?
After hearing the letter-box, I walked to the front door and stooped down to collect my latest edition of Eye News. I winced. Still, at least it would give me something to pass the time on this, my first day...
Importing iron to the retina
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...
Prophylaxis for clinical macular oedema after phacoemulsification
The authors report on a retrospective cohort study looking at three different prophylaxis methods for macular oedema after cataract surgery: 1) Topical prednisolone acetate (PA) alone; 2) Topical PA in combination with non-steroidal anti-inflammatory drug (NSAID); 3) Intraoperative subconjunctival injection...
Intravitreal aflibercept for diabetic macular oedema
The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...
Brn3b neuroprotective effect in rat glaucoma model
An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...
Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
Reduced angle after BT for postop diplopia test
The authors undertook a retrospective study to evaluate the extent of reduced deviation after Botulinum toxin (BT) when used as a postoperative diplopia test. They evaluated effect in 39 patients: 32 exotropia and seven esotropia. The same BT dose was...
Avastin vs. Volon A for diabetic macular oedema
This prospective randomised interventional clinical trial compared 30 diabetic patients with macular oedema treated with either intravitreal injections of bevacizumab (Avastin) or triamcinolone (Volon A). One group initially received three injections of 2.5 mg Avastin in monthly intervals whilst the...
Ointment related granulomas post-blepharoplasty
This is a retrospective review of eight patients who developed granulomatous masses after lower lid blepharoplasty. All patients had sutureless bilateral trans-conjunctival surgery, and lubricating ointment was instilled into the inferior fornix postoperatively for two days. Painless lower lid masses...
