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Low-dose bimatoprost/timolol gel: a new fixed-combination option

This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

Immunotherapy for orbital SCC

In the UK, cemiplimab is recommended for treating metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) in adults when curative surgery or curative radiotherapy is not suitable. Pembrolizumab is recommended as an option for untreated metastatic or unresectable recurrent...

Risks to visual function from blepharokeratoconjunctivitis

This study evaluated the prevalence of blepharokeratoconjunctivitis (BKC) and prevalence of amblyopic risk factors with comparison of these rates to rates in the general US paediatric population. The authors evaluated the rate of patient reported symptoms in patients with and...

Motor vehicle accident-related eye trauma trends in the United States

The authors present a large retrospective epidemiological study analysing motor vehicle accident-associated eye injuries presenting to US emergency departments between 2000 and 2020. Using a national injury surveillance database (NEISS-AIP), they examined incidence trends, patient demographics and injury patterns over...

What can artificial intelligence do to improve sustainability in the delivery of ophthalmic care?

The 2025 NHS 10-year plan, titled ‘Fit for the Future’, emphasises a significant shift from analogue to digital, with a strong focus on integrating AI and other technologies to transform healthcare. The plan aims to make the NHS the "most...

Supporting innovative eye disease research

Newmedica is supporting research into a potential next generation treatment for diabetic retinopathy, reinforcing its commitment as an eye health champion. Working in partnership with charity Sight Research UK, the project is led by Dr Michael O’Hare and his team...

Leadership skills training through the COECSA-RCOphth LINK

The Lead Forward project was an initiative of the VISION 2020 LINKS Programme, funded by the Department for International Development (DFID) via the Tropical Health Education Trust (THET). It aimed to improve the quality of medical leadership within VISION 2020...

My top five: Emerging alternatives to manage and treat nAMD

Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

My Top Five: Emerging alternatives to manage and treat nAMD

Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...