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663 results found

Microperimetry of subretinal drusenoid deposits

Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...

HtrA1 enhances cell senescence

A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...

Macular pigment and dark adaptation in older population with normal maculas

Macular pigment (MP) such as lutein, zeaxanthin and meso-zeaxanthin are highly concentrated in the fovea. They protect the retina from damage of ambient blue light via antioxidant properties. In older eyes with normal healthy retina, macular pigment optical density (MPOD)...

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Customised corneal crosslinking with supplemental oxygen

In this prospective interventional case series, the authors investigate using supplemental oxygen delivery during epithelium-on corneal crosslinking (CXL) with specially designed oxygen delivery goggles. Twenty-seven eyes of 24 patients underwent epi-on CXL with Riboflavin and Ultraviolet-A irradiation. At six months...

A paradigm shift: re-defining success in retinal detachment repair

The authors describe in this review article that functional outcomes vary with surgical technique for retinal detachment repair. Traditional definitions of surgical success have been shifted due to advances in imaging techniques. Assessment of the integrity of retinal reattachment including...

Ocular damage from laser pointers

This retrospective study of case notes from a tertiary eye centre over a five-year period, recruited nine children (12 eyes: eight boys) aged 9-15 years. Three presented with deteriorating vision whilst others had retinal changes noted as incidental findings at...

Two-year results of a T&E aflibercept regime in caucasian PNV

This a retrospective study examining two-year outcomes of patients with pachychoroid neovasculopathy (PNV) treated with a treat and extend (T&E) regimen of intravitreal aflibercept. The mean age was 63.84 ± 7.92 years with nine males (35%) and 17 females (65%)....

Features, treatment and prevention of conjunctival inclusion cysts

Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...

A novel parameter for angle closure

This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...

Ciclosporin and dry eye

Dry eye has an estimated prevalence of between 5 and 50% worldwide and has physical, psychological and socioeconomic consequences for the human population [1]. Loss of tear film homeostasis with associated ocular surface inflammation causes symptoms ranging from ‘tired’ eyes...

Feb/Mar 2017 Quiz

History A 40-year-old male patient presented with a right lower eyelid swelling with gradual enlargement for two months. On examination there was a large lesion apparently involving lid margin, part of palpebral conjunctiva and skin. No other local or systemic...