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Mast cells in Graves’ ophthalmopathy

Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

Acromegaly associated with enlargement of extraocular recti muscles

This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....

Descemetorhexis without endothelial keratoplasty

This retrospective study examined outcomes of the largest reported series of eyes, which underwent Descemetorhexis without endothelial keratoplasty (DWEK) for Fuch’s endothelial dystrophy with mean 10 months of follow-up. Seventeen eyes were included in analysis; with 82.4% achieving corneal clearance...

A surgical option for congenital ptosis

The authors describe a surgical technique to manage congenital ptosis. They present 30 patients with severe congenital ptosis, MRD1 varying between -2mm and 1mm. Intervention was carried out early to prevent amblyopia. All cases had surgery before age seven with...

Haag-Streit UK moves to exciting new premises

Haag-Streit UK is pleased to announce that they have moved their UK headquarters from Harlow to Bishop’s Stortford (Hertfordshire).

Trainee personality types

Over the past two years I have attended quite a number of medical educational seminars and ‘workshops’ and have been a bit shocked at how out of kilter with reality the world of education seems to be now. It seems...

How do you solve the problem of trachoma in Ethiopia?

Background Trachoma is one of the oldest diseases known to humankind and the leading infectious cause of blindness worldwide. Spread by the bacterium chlamydia trachomatis, it is transmitted through contact with the eyes, eyelids and nose of those infected. The...

Expensive Malware

Cryptolocker and similar ransomware There is a new breed of computer malware that is spreading rapidly. The first major manifestation of this new type is known as Cryptolocker. At present it’s a Windows only problem (all versions), but it’s likely...

What's trending Oct/Nov 2022

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #teammates #warringtonwolves #keratoconus Robbie Mulhern, a professional rugby league player for Warrington Wolves, had never heard of keratoconus prior to...

The Lily Foundation celebrates approval of first ever mitochondrial disease treatment by NICE

The Lily Foundation, the UK’s leading mitochondrial disease charity, is today celebrating a landmark achievement in the fight against the disease – the first ever treatment for a mitochondrial condition has been approved for use on the NHS in England....

Orbital Schwannomas

This is a large case series of orbital Schwannomas managed at a single centre over a 26-year period. Twenty Schwannomas are reported, all but one of which was managed surgically. The tumours were all benign, had an insidious onset and...