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Non-infectious Uveitis: Well Known, Weird and Wonderful meets You, Me and the Balloons

Installation view from Manchester International Festival 2023 exhibition Yayoi Kusama: You, Me and the Balloons at Aviva Studios. Images © David Levene. On an uncharacteristically salubrious 5 July 2023, the date of the 75th Anniversary of the UK’s NHS, a...

Mast cells in Graves’ ophthalmopathy

Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

Acromegaly associated with enlargement of extraocular recti muscles

This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....

Descemetorhexis without endothelial keratoplasty

This retrospective study examined outcomes of the largest reported series of eyes, which underwent Descemetorhexis without endothelial keratoplasty (DWEK) for Fuch’s endothelial dystrophy with mean 10 months of follow-up. Seventeen eyes were included in analysis; with 82.4% achieving corneal clearance...

A surgical option for congenital ptosis

The authors describe a surgical technique to manage congenital ptosis. They present 30 patients with severe congenital ptosis, MRD1 varying between -2mm and 1mm. Intervention was carried out early to prevent amblyopia. All cases had surgery before age seven with...

Expensive Malware

Cryptolocker and similar ransomware There is a new breed of computer malware that is spreading rapidly. The first major manifestation of this new type is known as Cryptolocker. At present it’s a Windows only problem (all versions), but it’s likely...