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3409 results found

Do topical steroids improve visual outcome in the treatment of bacterial keratitis?

The use of topical corticosteroids as an adjunctive treatment to antibiotics in the management of bacterial keratitis remains a controversial issue. The results of the Steroids for Corneal Ulcers Trial (SCUT) – a randomised, double-masked, placebo-controlled trial that recruited patients...

Outcomes of corneal collagen crosslinking (CXL) in pseudophakic bullous keratopathy (PBK)

This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...

Hypothyroidsim and acute central serous chorioretinopathy – is there a link?

This cross-sectional study included 71 consecutive acute central serous chorioretinopathy (CSC) patients and 70 age-matched healthy control subjects. Systemic findings, including serum levels of thyroid hormones, thyroid stimulating hormone (TSH), mean arterial pressure (MAP), pulse rate, serum lipid levels and...

Multicentre PCO rates in different brands of monofocal intraocular lenses

This was a longitudinal, retrospective cohort study featuring 47,754 (three years) and 20,763 (five years) eyes with age-related (≥65 year) cataract surgeries between 2010-2013 across seven UK ophthalmology clinics. The three- and five-year incidence of posterior capsular opacification (PCO) and...

The eyes of healthy children effected by virtual schooling

The authors aimed to assess how the increased use of technology during a day of virtual school as a result of the COVID-19 pandemic affected the eyes of healthy children. Children aged 10 to 17 years who attended school virtually...

Significant associations to presence of significant retinal haemorrhages in suspected child abuse

The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...

Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?

The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...

Does paediatric rhegmatogenous retinal detachment (RRD) obey Lincoff’s rule (LR)?

This was a retrospective study where 98 paediatric patients with RRD were identified through surgery records. Forty case sheets with complete record of ocular examination and surgical findings were analysed. Visible or suspected preoperative retinal break identified using the LR...

Visual acuity improvement in amblyopic eyes following fellow eye vision loss

The authors present a systematic review with the aim of reporting how frequently and to what extent amblyopia recovers following the loss of vision in the fellow eye and identify any potential clinical predictors. Studies including adults with amblyopia and...

More action on sepsis needed as NHS Ombudsman still seeing same failings a decade on

The UK’s Health Ombudsman has warned that sepsis is still taking too many lives due to the same hospital failings we were seeing over ten years ago.

Genetic therapy gives infants life-changing improvements in sight

Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Profile of a tertiary referral oculoplastics service in the UK

The provision of safe and effective ophthalmic care to large patient populations has always been challenging. Severe restrictions of outpatient clinical activity due to the COVID-19 crisis has compounded this problem, with 26,800 appointments cancelled in our unit in the...