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A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...

Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma

Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...

Does Ozurdex affect perfusion status in vein occlusion?

Ozurdex (intravitreal dexamethasone implant) has been approved by National Institute of Health & Care Excellence (NICE) for treatment of patients with macular oedema associated with vein occlusion. This study looks at the change in peripheral perfusion status in patients with...

Disc margin delineation using spectral domain OCT

Observing progressive anatomical changes of the optic nerve head is essential in the detection of progression in glaucoma. Imaging devices continue to evolve and are useful in detecting change in established glaucoma, although probably less useful in an initial diagnosis....

Manometric tear duct irrigation system against the conventional lacrimal syringing

The authors assessed the lacrimal outflow resistance with a modified irrigation system. The manometric tear duct test (mTDT) comprised of a 6mm thin wall 25 gauge lacrimal cannula which was attached to a bag of normal saline by standard fluid...

Near-infrared autofluorescence to diagnose retinal laser injuries

This retrospective observational case series aimed to assess whether near infrared autofluorescence (NIR-AR) imaging is a useful imaging modality in the diagnosis of hand-held laser retinal injuries. Twelve patients from two centres underwent ophthalmic assessment and retinal imaging including fundus...

Corneal and astigmatic changes after medial rectus recession surgery of 6mm

This study prospectively compared changes in astigmatism before and two months after unilateral recession of medial rectus muscles using Pentacam. The fellow unoperated eye was used as the control eye. The study included 66 eyes and 33 patients; 21 males,...

AI predicts eye damage from autoimmune drug, years before symptoms appear

A novel AI tool could transform screening for patients taking hydroxychloroquine by spotting early signs of eye damage, according to a study published in Opthalmology Retina. Researchers have devised an artificial intelligence (AI) system that can detect and predict serious...

RCOphth Research Changes Lives

The Royal College of Ophthalmologists Research Changes Lives

Clearly: How a 700 year old invention can change the world forever

“If you are reading this, there’s a one in two chance that you’re doing so with a pair of glasses or contact lenses. Just imagine what your life would be like without them.” Most of the people living in this...

Ombudsman comments on Letby inquiry's statutory status

Parliamentary and Health Service Ombudsman Rob Behrens comments on the Letby inquiry being given statutory status.

Uveitis and juvenile arthritis costs

The purpose of this study was to evaluate whether cost, prior insurance authorisation concerns and subspecialty practice influence therapeutic decisions in the treatment of uveitis associated with JIA. The authors developed an email questionnaire that included a brief vignette of...