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Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...
Eye journal cover image.

Ranibizumab safety in pregnancy

1 December 2018 | | EYE - Vitreo-Retinal
Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...
Cornea journal cover image.

How long to air tamponade after DMEK?

1 April 2019 | | EYE - Cornea, EYE - General
This interventional case series looked at the influence of different intraoperative air tamponade times on graft adherence after descemet membrane endothelial keratoplasty (DMEK). A total of 117 eyes with Fuchs endothelial corneal dystrophy (FECD) that underwent DMEK were included. Patients...
Ophthalmologica journal cover image.

Autofluorescence patterns in subretinal haemorrhages associated with neovascular age-related macular degeneration

2 August 2024 | | EYE - Vitreo-Retinal
The aim of this retrospective study was to describe the surgical results and fundus autofluorescence (FAF) patterns occurring in sub-macular haemorrhage (SMH) of duration <60 days in age-related macular degeneration (AMD). Notes from 39 eyes of 39 patients with SMH,...
Ophthalmologica journal cover image.

Type 3 macular neovascularisation (MNV) due to age-related macular degeneration

3 October 2024 | | EYE - Vitreo-Retinal
This paper systematically reviews and summarises the current knowledge on type 3 neovascularisation due to age-related macular degeneration which is defined as neovascularisation originating from the retinal deep capillary plexus that grows towards the outer retina often penetrating the level...

In conversation with Fares Antaki: The retinal age gap in schizophrenia

3 April 2026 | | EYE - Vitreo-Retinal
Fares Antaki. Nima Ghadiri (NG): The ‘retinal age gap’ (RAG) is a relatively new concept. Based on your study [1], how confident are you in proposing this as a non-invasive, accessible biomarker for accelerated biological ageing in patients with neuropsychiatric...

Crombie comes home: Tips and hacks for the FRCOphth Part 1

3 June 2026 | | EYE - General
This article offers a reflection on preparation, strategies and insights gained while preparing for a first exam encounter: the FRCOphth Part 1. Preparing for the FRCOphth Part 1, the first major hurdle on the path to fellowship of the Royal...

Around 450,000 children disadvantaged by lack of school support for colour blindness

5 December 2024 | colour blindness, eyesight, SEND, education, children, school, book
Around 450,000 children are being failed by the UK education system because they have a special educational need and disability (SEND) that is effectively unrecognised by most schools and local education authorities, an author has warned. Supporting Colour Blindness in...

Should it be a mandatory requirement for medical students to receive the COVID-19 vaccine to attend clinical attachments?

7 April 2021 | | EYE - General
The vast majority of medical students have positive attitudes towards the COVID-19 vaccine for themselves and patients, however, what about the small inevitable minority who resist it? Should they be prevented from attending clinical attachments in the NHS? It is...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

1 October 2014 | | EYE - Cornea
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Patient safety – is this achieved in optometry with CET?

1 August 2018 | | EYE - General
Collecting points and ticking boxes – as we come to the end of another three year cycle of continuing education and training (CET), the rush to ensure that everything has been completed on the myGOC (General Optical Council) dashboard feels...

Money is a problem, but the problem is bigger than money

3 February 2026 | | EYE - General
The argument surrounding doctors’ pay remains an ongoing battle. At the time of writing, Foundation Year 1 doctors have voted in favour of industrial action due to the lack of substantive employment or regular locum work at the end of...