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Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients
This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...
Understanding the pachychoroid disease spectrum
This article provides a comprehensive review of the pachychoroid disease spectrum, a group of chorioretinal disorders characterised by abnormal choroidal thickening and various pathological changes in the choroid, retinal pigment epithelium, and retina. It also highlights the controversies and knowledge...
Cataract surgery in the extremely small eye: morphology, comorbidities and outcomes in 300 eyes
This is a retrospective study from Heidelberg University, Germany, between January 2009 to October 2023, including 300 eyes of 191 patients undergoing cataract surgery with short axial length requiring lens implantation of > 30 dioptres. Eyes were classified into the...
Understanding optic nerve head pericytes and glaucoma
The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...
Results of bilateral medial rectus recession combined with either BT or bridge Faden when treating large angle strabismus
In a series of 26 patients (11 female, 15 male) with large angle esotropia >35PD, the authors compared results of botulinum toxin A (BTA) and bridge Faden operation combined with bilateral medial rectus (BMR) recession. Overall age of surgery was...
Use of immunomodulatory treatment for non-infectious uveitis: an International
Two-hundred-and-twenty-one group members from 53 countries completed a questionnaire on their indications, investigations and use of conventional and biologics and follow-up of treated patients. Main indications to start systemic immunomodulatory drugs were: uveitis not controlled by oral prednisolone (94.1%), specific...
Retinal thickness and visual acuity change correlations after amblyopia occlusion therapy
This prospective study aimed to assess change in retinal nerve fibre layer (RNFL) and macular thickness, and clinical correlations with visual outcomes, after amblyopia treatment in 30 children with moderate to severe amblyopia. Mean age of children was 5.26 ±1.65...
Lebanese refractive amblyopia risk factors within school systems
This study investigated the frequency and types of refractive amblyogenic risk factors in a community-based cohort of Lebanese children aged 3–6 years with comparison of public and private school students. The study included 990 students (1980 eyes): 278 public and...
AI glaucoma screening cost-effective in the Netherlands?
Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...
Quality of Instagram posts about amblyopia
The purpose of this study was to better understand the availability, accuracy and extent of information available on Instagram about amblyopia. The authors evaluated content of the top 200 publicly available Instagram posts about amblyopia from October–December 2022. Posts were...
Surgical outcomes of primary recess/resection vs readvancement/recession surgery for exotropia
This study compared the surgical yield of primary lateral rectus and medial rectus recession/resection (RR) surgery for basic exotropia, convergence insufficiency type exotropia (CIXT) and divergence excess (DXS) vs. patients undergoing medial rectus readvancement (MRR) +/- lateral rectus recession for...
