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A comparative evaluation of a new diffractive trifocal and EDOF IOLs

This study aimed to compare the outcomes of two diffractive trifocal intraocular lenses and one extended depth of focus (EDOF) intraocular lens (IOLs). This was a six month, single centred, prospective, randomised, comparative study in which patients who underwent routine...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Intravitreal injection related endophthalmitis

This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

Ranibizumab versus laser in diabetic macular oedema (LUCIDATE study)

The aim of this study was to compare the functional and structural effects of Ranibizumab versus macular laser treatment in patients with diabetic macular oedema. It was a single centre, prospective, randomised, single masked clinical trial spanning a 48 week...

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Effectiveness of supramaximal horizontal surgery for third nerve palsy

The purpose of this study was to present the outcomes and progress of third nerve palsy cases after supra-maximal recession / resection. The aim is for an initial overcorrection of 15-25PD at day one. This was a retrospective study of...

Prediction of recurrence in exotropia

This study compares the long-term motor and sensory outcomes between constant and intermittent exotropia in infancy and investigated whether constancy can be used as a reliable factor for predicting surgical outcomes. Sixty-seven patients were reviewed – 37 constant and 30...