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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Closed-chamber haptic re-externalisation for posteriorly displaced sclerotomy and inadequate haptic tuck in glued posterior chamber intraocular lenses

This technique (online video http://jcrsjournal.org) emphasises the importance of both symmetrical and sufficient anterior placement of sclerotomies to externalise an adequate length of the haptics, which in turn provides good centration and stability of the intra-ocular lens (IOL). The authors...

Reduction of severe visual loss and complications following IAC for RB

This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...

Intravenous ketorolac during DCR

This study compares pain scores postoperatively between patients that received intravenous ketorolac (IVK) pre, intra or immediately postoperatively and a control group that did not receive it. The authors state that the patients were randomised, however it is not described...