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Does Acanthamoeba need bacteria to cause keratitis?

An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...

Outcomes of primary and repeat DSAEKs

Retrospective analysis of results following primary and secondary descemet stripping automated endothelial keratoplasty (DSAEKs), carried out in Villa Serena-Villa Igea Private Hospitals in Italy, showed that primary and secondary DSAEK surgery result in similar visual outcomes, refractive errors and endothelial...

Corneal tattooing as treatment for bullous keratopathy

This retrospective study looked at differences in epithelial smoothing in patients with bullous keratopathy (BK) undergoing either corneal tattooing or anterior stromal puncture (ASP). Both procedures were carried out for symptomatic relief in eyes with poor visual potential. Chinese ink...

Effect of voriconazole of vision of healthy volunteers

Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...

Beliefs and adherence to glaucoma treatment

The aim of the study was to determine adherence rates and beliefs about glaucoma and its treatment in white Americans, African Americans, white Australians and Singaporeans of Chinese descent. A cross-sectional study of 475 glaucoma patients using topical eye drops...

Lens surgery in patients with lens subluxation misdiagnosed as primary angle-closure glaucoma

Lens subluxation can be caused by many conditions including Marfan syndrome and other hereditary conditions, and blunt trauma. Lens displacement can cause pupillary block and angle closure. This is commonly misdiagnosed as primary angle closure glaucoma (PACG), which can lead...

Telemedicine retinopathy of prematurity (ROP) screening

The Auckland Regional Telemedicine ROP network utilises wide-field digital imaging for ROP screening. Results are from 2006-2015; 1181 infants were screened over three neonatal intensive care units; 83 infants with ROP were identified. Screening rates increased over the 10 years...

Nepafenac punctal plugs after cataract surgery: a new alternative?

The nepafenac punctal plug delivery system (N-PPDS) is an experimental L-shaped plug made of nonbiodegradable, preservative-free medical-grade silicone. It can deliver a sustained level of nepafenac for six weeks. This is a prospective, randomised, parallel-arm, double-masked, placebo-controlled, phase II pilot...

The incidence of sympathetic ophthalmia

In this meta-analysis, the authors looked at 24 retrospective studies to determine the incidence of sympathetic ophthalmia following open globe injury amongst adult and paediatric populations. The year of publication of studies included ranged from 1972-2019, and with broad search...

Using optical coherence tomography angiography to detect MoyaMoya vasculopathy

Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...

Changes in the prevalence of myopia in middle-aged caucasian Australians compared to UK biobank

This article compares rates of myopia and high myopia in large cohorts of caucasian Australians from the Busselton Healthy Ageing Study, the urban Gen1 of the Raine Study, the Blue Mountains Eye study and Melbourne Visual Impairment Project. The former...

Insights on medical AI for ophthalmology: an update on current perspectives

Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...