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Presenting and diagnostic signs of retinoblastoma

This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...

Orbis UK release 2024 highlights video

Orbis UK have released their 2024 highlights video, revealing some of the incredible achievements their supporters helped make possible last year. The Orbis Flying Eye Hospital completed two sight-saving missions to Mongolia and Bangladesh. Orbis's clinical staff and Volunteer medical...

The 2024 #AspireOphth Competition

The RCOphth 2024 Annual Congress / #EyeConUK is coming up and you know what that means, we're teaming up again with Sohiab R Rufai for another #AspireOphth Competition!

The 2025 #AspireOphth Competition

That's right, we’re going to be running our fourth edition of the #AspireOphth competition, in which entrants have the opportunity to share an image which accurately reflects their aspirations in ophthalmology for a chance to win a prize. The two...

3rd Annual Retinal Imaging Biomarkers & Endpoints Summit

Accelerate Your Ophthalmic Development with Deep Learning Systems & Sophisticated AI Imaging TechnologiesWith state-of-the-art AI-assisted technology making retinal imaging 100 times faster, the rapid advancement of technology in ophthalmology, coupled with the strong unmet need for more drugs for retinal...

The inflammatory side-effect of Brimonidine

Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...

Bioengineered human tissue

This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...

New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Management and outcomes of congenital fibrovascular pupillary membranes (CFPM)

Congenital fibrovascular pupillary membranes (CFPM) is defined as a white fibrous membrane across the pupil which may be an ectopic iris tissue arising from the aberrant migration of neural crest cells or a variant of persistent fetal vasculature. The authors...

Does Duane syndrome have an effect on refractive error?

The authors present a retrospective case review from a database created from a 43-year period of patients with strabismus seen by a single ophthalmologist. Cases were reviewed by either an orthoptist or ophthalmologist for entry into the database. Details relating...

Efficacy of BT as a treatment for cranial nerve palsy in acute and chronic cases

The authors performed a meta-analysis of all patients’ treatment with botulinum toxin (BT) for cranial nerve palsy (CNP) to determine the efficacy of BT in the treatment of CNP due to a variety of causes. The search identified 1129 articles...

Polymerase chain reaction evaluation of infectious multifocal serpiginoid choroiditis

This paper presents a retrospective review of infectious agents associated with multifocal serpiginous choroiditis (MSC) based on polymerase chain reaction (PCR) evaluation and specific antimicrobial therapy. The study included 13 patients with MSC who were evaluated with PCR for the...