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Audiology and ophthalmology: A comparative perspective on diagnostics and patient care
4 December 2024
| Rosalyn Painter, Christopher Gordon, Anthony Vukic
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EYE - Imaging, EYE - Vitreo-Retinal
I’m here with Chris Gordon and Anthony Vukic from Gloucestershire Hospitals NHS Foundation Trust to find out how two professions that may appear unrelated on the surface actually have a lot in common. Some of this article might surprise you....
What not to miss in neuro-ophthalmology Part 1
1 April 2018
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EYE - Neuro-ophthalmology
Neuro-ophthalmology is a complex and difficult subspecialty in ophthalmology. It has several connections to neurology, neuro-surgery, rheumatology as well as many other medical specialties. Working in an multidisciplinary team (MDT) environment is key to success in this subspecialty as mistakes...
Recurrent unilateral preseptal cellulitis secondary to herpes simplex virus infection
3 April 2023
| Shaheryar Ahmed Khan, Bridget Hemmant, Radomir Babovic, Yomi Imasogie
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EYE - General
Introduction Periorbital (sometimes called preseptal cellulitis) is a common condition which on its own is not normally an ophthalmic or surgical emergency, however it has the potential to cause severe and serious morbidity in cases where the infection has crossed...
Shedding light on Wolfram syndrome: The unveiling of a delayed diagnosis
12 August 2025
| Valeria Antoniou, Sonia Kafkalia, Katerina Papastavrou, Theodoros Potamitis, Antigoni Koukkoulli
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EYE - Neuro-ophthalmology
Wolfram syndrome 1 (WS1) was first described by Wolfram and Wagener in 1938 and it’s a rare neurodegenerative, progressive disorder, also known as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) [1]. We present an atypical case of WS...
A near miss
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...A standardised strategy for uveitis etiological diagnosis
1 August 2017
| Efrosini Papagiannuli
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EYE - Vitreo-Retinal
This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...
American Academy of Ophthalmology – Updated textbooks Basic and Clinical Science Course 2018-2019
The American Academy of Ophthalmology publish a series of books entitled Basic and Clinical Science Course every year. It’s a highly regarded series and has often been quoted to me as a good reference set of books. Indeed, I invested...Sneak peek: UKISCRS Cornea & Cataract Day 2025
We're excited to be attending UKISCRS' Cornea & Cataract Day in Liverpool on 19 May. Here's a quick 'sneak peek' into what's in store by our editor and UKISCRS President, David Lockington...Upper eyelid ulceration as a presenting sign of frontal sinus mucocele
3 October 2022
| Mustafa Al-Hashimi, Ranad Maswadi, Bijan Beigi
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EYE - General
Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...
Jun/Jul 2015 Quiz
1 June 2015
| Hardeep Singh Mudhar
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EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 35-year-old male presents with bilateral corneal opacities. Examination shows a honeycomb-type dystrophy. A penetrating keratoplasty is performed and the specimen sent for ophthalmic histopathological assessment. Figure 1 is the haemotoxylin & eosin (H&E). Figure 2 is a Masson...
Stromal cell alignment in damaged cornea
1 August 2017
| Graham Wallace
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EYE - Cornea, EYE - General
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Confocal microscopy, Corneal wound healing, Extracellular matrix, SHG imaging
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
1 October 2016
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...