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Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Hypothyroidsim and acute central serous chorioretinopathy – is there a link?

This cross-sectional study included 71 consecutive acute central serous chorioretinopathy (CSC) patients and 70 age-matched healthy control subjects. Systemic findings, including serum levels of thyroid hormones, thyroid stimulating hormone (TSH), mean arterial pressure (MAP), pulse rate, serum lipid levels and...

Supporting the next generation of ophthalmologists. That’s Newmedica.

Independent provider Newmedica offers placements in centres nationwide, supporting ophthalmologists in training. Both trainees and consultants have noted the benefits for patients and the NHS, with the North East programme as a prime example. Dr Oonagh Crothers, a fifth year...

Fight for Sight continues to promote eye research

Eye research charity Fight for Sight has announced its latest project funding and its plans for continuing its efforts to advance eye research in the current global health crisis and beyond.

Effective treatment for rare sight-threatening infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...

Advanced level practice for ophthalmic nursing

The Royal College of Nursing (RCN) Ophthalmic Nursing Forum (ONF) is committed to clinical excellence through advancing ophthalmic nursing practice and supporting career development. With the increasing demand for ophthalmic services, advanced and specialist practice roles are vital to increase...

Ophthalmology survey results August/September 2019

I am delighted to see another great response to the practice variance survey. I am extremely grateful to all of you who took part and would encourage those of you who didn’t to try this survey. It literally takes mere...

Don’t ignore the black lesion! It might be mucormycosis

Keeping mucormycosis infection in the foreground of your differential diagnosis, especially in those more vulnerable patients, will help save their lives if recognised and managed appropriately. Mucormycosis is a fulminant infection caused by the fungi of the family Mucoraceae. It...

Newmedica calls for transparency over glaucoma waiting lists and more collaboration with community optometrists

Ophthalmology provider Newmedica is calling for greater transparency by all providers over glaucoma waiting lists to tackle a ‘postcode lottery’ facing patients. Coinciding with Glaucoma Awareness Week (30 June – 6 July), Newmedica, which provides NHS and private ophthalmology services,...

The natural history of treatment naïve choroidal neovascularisation (CNV) in geographic atrophy

The aim of this retrospective study is to assess the characteristics and natural history of quiescent CNV in geographic atrophy (GA) utilising multi-modal imaging. Case notes were reviewed of patients diagnosed with geographic atrophy between January 2010 and December 2016...