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Corneal molecular and cellular biology for refractive surgeon
This is an interesting literature review that looks into the recent advances concerning the corneal molecular and cellular processes that are involved in the wound healing response after excimer laser surface ablation and LASIK surgery. It talks about the complex...
Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
Conjunctival inflammation in glaucoma patients
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
Use of amniotic membrane in second stage Hughes tarsocunjunctival reconstruction
This is a retrospective, non-comparative interventional case series of 30 patients who underwent amniotic membrane transplantation to lower lid margin as part of Hughes lid reconstruction to prevent a hyperaemic, hypertrophic conjunctival margin with excessive discharge. Patients undergoing more than...
Review of the use of amniotic membrane in restrictive strabismus
This literature review was undertaken to investigate the indications, complications and final results of amniotic membrane (AM) transplantation in ocular motility restrictions. The review (of 1103 papers) outlines the healing process plus use of AM. Excluded papers were those of...
Adjunct amniotic membrane during enucleation for retinoblastoma to prevent implant exposure
Amniotic membrane (AM) has potential for treatment of retinoblastoma (RB) patients with contracted sockets after enucleation. The authors present their experience of AM with enucleation for patients with RB after chemotherapy in this retrospective study of 100 eyes of 107...
Myopia progression with atropine and different treatment lenses
This study aimed to determine the effectiveness of low dose atropine at inhibiting myopia progression, the possible additive potency of this treatment combined with either of two peripheral defocus contact lenses over three years of therapy, and whether there was...Addressing diabetes-related complications in Tanzania and Eswatini: A comprehensive approach to eye and foot screening
Diabetes is rising globally, particularly in low- to middle-income countries (LMICs), where healthcare systems are under resourced [1,2]. Among its complications, diabetic retinopathy (DR) and diabetic foot disease are preventable yet frequently overlooked [3-6]. These problems often develop together due...The results of the last survey Jun24
When I was in my training and even in my early years as a consultant, I did not fully understand the difference between different lenses. When asked my preference of hydrophilic versus hydrophobic intraocular lenses (IOLs) I really did not...Is optician led service an answer to ever increasing demand on eye emergency clinics?
The demand for eye casualty appointments has been steadily increasing in the UK, leading to pressures on the hospital emergency services. The incidence of presentations to eye casualty services has been estimated at 20-30 per 1000 per year [1]. Evidence...Moorfields: Orthoptics for ophthalmologists
This blended orthoptic course has been designed by experienced orthoptists at Moorfields Eye Hospital and is suitable for all doctors undertaking the FRCOphth Part 2 exams or for anyone wishing to improve their orthoptic skills. Course stuctureThere are six narrated...
