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The impact of collagen crosslinking on keratoplasty numbers in keratoconics
A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...
Rituximab as an immunosuppression treatment for thyroid eye disease
Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...
Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study
Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...
The long-term effects of AREDS on AMD progression
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
Surgery for unilateral superior oblique palsy
This study evaluates the amount of effectiveness of inferior oblique myectomy in primary position, lateral gaze and head tilt, and the effect on improving extent of abnormal head posture. The study included 39 patients; 22 male, 25 left-sided palsy and...
Preoperative anxiety levels and pain during cataract surgery
Increased anxiety has been shown to be associated with greater pain in a number of procedures. In this observational, non-interventional study, the authors sought to evaluate the correlation between pain with phacoemulsification surgery (under topical and intracameral local anaesthesia) and...
Tetracaine to reduce OCR
This study investigates the effects of Tetracaine eye drops on oculocardiac reflex (OCR) during strabismus surgery. A randomised controlled trial of 70 strabismus surgery patients aged two to 19 years was conducted with comparison of Tetracaine versus placebo. Demographics were...
Use of Bagolini filter bars
The authors measured the percentage light transmission of filters on different Bagolini filter bars to evaluate whether a difference exists in density of suppression or strength of abnormal binocular single vision (BSV). A Sekonic dual spot photometer was used to...
Effect of caffeine and low intensity endurance exercise on intraocular pressure
This placebo controlled, double blind, balanced crossover study reports in healthy individuals that 30 minutes of cycling caused a maximum of 2.7mmHg lowering of IOP. A caffeine dose of 4mg/kg 30 minutes prior to cycling negated this effect. The conclusion...
Impact of amblyopia on adult planning and problem solving
This study sought to evaluate whether monocular amblyopia has an impact on planning and problem solving in the adult population. The authors used the Tower of London (TOL) test to address this question. The TOL test was developed to assess...
Orbital cavernous haemangiomas
This is a review of orbital cavernous haemangiomas (orbital cavernous venous malformations) managed over a 12-year period at a tertiary referral centre. Painless proptosis was the commonest presentation. One hundred and sixty-four patients (96 female and 68 male) underwent surgery...
