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Is thrombolytic treatment warranted for central retinal artery occlusion?
Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke which results in severe visual loss. Acute CRAO is equivalent to a brain acute ischaemic stroke (AIS), as the obstruction of the central retinal artery (CRA) causes end-organ...
Review of efficacy and safety of tetracaine drops in strabismus surgery
Tetracaine is a topical anaesthetic drug used to anesthetise the eye and surrounding areas during strabismus surgery. It is generally safe and well tolerated but can cause mild adverse reactions at the site of use and, in rare cases, serious...
Orbital fat density as a diagnostic tool in pre-septal and orbital cellulitis
This study aimed to evaluate the usefulness of orbital fat density in identifying post-septal involvement when initial differential diagnosis between orbital (OC) and periorbital (POC) cellulitis is unclear. This was a retrospective study of 57 patients with clinical diagnosis of...
Types of nystagmus and associations in a large international database for nystagmus
The authors aimed to characterise a large international cohort of children with nystagmus. Data were taken from a prospective database which was started in 2010. Up to 2020, this contained 1774 patients with nystagmus from 38 US states and 30...
Updated staging of LCHADD retinopathy
The authors present their proposal for an updated staging system for Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase (LCHAD) deficiency retinopathy. This is a rare mitochondrial disease due to deficiency of the long chain fatty acid oxidation pathway. Forty patients who were part of...
Ahmed and Baerveldt glaucoma drainage implant outcomes
This study reports the surgical outcomes of both the Ahmed (AGV) and Baerveldt (BGI) glaucoma drainage implants in a cohort of patients with primary congenital glaucoma over a long follow-up in a single tertiary centre. This was a retrospective study...
BT vs primary surgery for infantile esotropia
In this study, the success rate of treatment for infantile esotropia (IET) patients who had surgery because of under correction after botulinum toxin (BT) is compared to those having primary surgery. The study included 52 patients (27 male) with mean...
Long-term treatment for diabetic macular oedema
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
Congenital nasolacrimal duct obstruction in patients with craniofacial abnormalities
This is a retrospective study including 1998 patients over a period of 10 years. Of this number, 41 patients were identified as having a craniofacial abnormality and congenital nasolacrimal duct obstruction (CNLDO) (23.1 per 10,000 live births). Interestingly the most...
Treatment for chronic severe bilateral blepharokeratoconjunctivitis
This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...
Retrospective analysis on the outcomes of contact lens-associated keratitis in a tertiary centre
This is a retrospective cohort study of 161 eyes (153 patients) with contact lens-associated keratitis (CLAK) from Moorfields Hospital between 1 July 2021 to 28 February 2022. They were classified into three groups based on the size of the epithelial...
