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Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

The results of the last survey Oct21

This edition’s survey questions moved away from the deep and ethically charged questions of the recent surveys and focussed on simple and straightforward issues. This is really where the surveys began in exploring the minor practice variations which we have...

Unexplained vision loss following exposure to combat

Non-organic vision loss (NOVL) is defined as a decrease in visual acuity or visual field without an identifiable organic cause. NOVL can be particularly challenging and time-consuming to diagnose, especially where the vision loss is superimposed on an element of...

Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients

For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...

As Far as the Eye Can See: A History of Seeing

I am a big fan of books which provide a historical context to some of the greatest wonders and challenges that we face. Siddarhtha Mukherjee does this well in Emperor of All Maladies (2010), where he explores the story of...

Comparison of visual field indices between normal adults and children

The authors present a prospective observational study which aimed to compare visual field indices with retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT) in normal adults and children. Children aged 6–18 years were recruited from a single...

Does delayed strabismus surgery have an association with psychiatric diagnoses in children?

The authors present a retrospective cohort study with the aim of assessing the association between strabismus surgery in early childhood and psychiatric diagnosis incidence. An international healthcare records platform was utilised to access electronic medical records from 92 healthcare organisation....

Conjunctival mapping biopsies in sebaceous carcinoma

This is a retrospective review of conjunctival mapping biopsies in patients with periocular sebaceous cell carcinoma. The authors reviewed the biopsy technique and outcomes of 45 patients who had mapping biopsies performed over a 25-year period. A total of 429...

LASEK vs. epi-LASIK for myopia: meta-analysis

Previous studies have produced inconsistent conclusions on the relative benefits between LASEK vs. Epi-LASIK. LASEK uses 20% alcohol to separate an epithelial flap from the Bowman membrane. After ablation, the epithelial flap is repositioned onto the cornea. Epi-LASIK creates the...

The impact of collagen crosslinking on keratoplasty numbers in keratoconics

A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...

Prediction of visual outcome in IIH

In this prospective study, visual outcome of 40 patients with idiopathic intracranial hypertension (IIH) was compared with clinical and neuro-ophthalmic parameters. The purpose of this was to determine any correlation to try and predict visual outcome for IIH patients. Parameters...

Carcinoid tumours

This is a retrospective review of 28 patients with carcinoid tumours affecting the orbit. The mean age at presentation of the orbital involvement was 62 years, with a slight female preponderance, and 21% had carcinoid syndrome. Proptosis and diplopia were...