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Effect of syringe-filling technique and risk for endophthalmitis after intravitreal injection of anti-VEGF agents

In this retrospective study the authors compare the risk for post-injection endophthalmitis between different anti-vascular endothelial growth factor (VEGF) agents and syringe preparation technique. This multicentre study included 197,402 injections. The drugs included in this study were three Anti-VEGF agents...

My Top Five: Red flag presentations all resident doctors must know

Ophthalmic emergencies are time-critical situations where delays in recognition or management can lead to permanent vision loss [1]. For resident doctors and medical students, identifying these red flags can be daunting, especially given the complexity of the eye and its...

A standardised strategy for uveitis etiological diagnosis

This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...

Outcomes of corneal cross-linking in paediatric patients compared to fellow untreated eyes

This retrospective cohort study evaluated long-term visual, refractive, topographic and safety outcomes of corneal cross-linking (CXL) in patients younger than 18-years-old with keratoconus. The study included all consecutive paediatric patients who underwent epithelium-off CXL treatment for keratoconus at the study...

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

50 Studies Every Ophthalmologist Should Know

This book features a compilation of 50 important clinical studies that have left a profound impact on the current clinical practice of ophthalmology. From the 1980 botulinum toxin injection study by AB Scott to the United Kingdom Glaucoma Treatment Study...

5-FU vs. Avastin as adjunct to conjunctival autograft

The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...

Does the length of the school day have a role in age of myopia onset?

The authors prospectively collected the refractive data of myopic adults attending recruiting dispensing optician or ophthalmologist sites. Participants were recruited consecutively, giving verbal informed consent. Sites included a mix of urban and rural areas across eight sites. The following data...