You searched for "inflammation"
Nanoparticle administration of latanoprost
Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...
Use of amniotic membrane in second stage Hughes tarsocunjunctival reconstruction
This is a retrospective, non-comparative interventional case series of 30 patients who underwent amniotic membrane transplantation to lower lid margin as part of Hughes lid reconstruction to prevent a hyperaemic, hypertrophic conjunctival margin with excessive discharge. Patients undergoing more than...
IgG4-related disease or Graves orbitopathy
This is retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...
Thyroid eye disease and obstructive sleep apnoea
This is a retrospective study looking for an association between compressive optic neuropathy in thyroid eye disease (TED-CON) and obstructive sleep apnoea (OSA). One hundred and nine patients with thyroid eye disease were asked to complete a validated questionnaire designed...
Intraocular pressure reduction after cataract surgery
Several studies have shown the efficacy of cataract surgery in lowering intraocular pressure (IOP), especially in angle closure glaucoma compared to open angle. A total of 156 eyes of 109 patients (without glaucoma or with medically controlled glaucoma) were included....
A novel presentation of optic disc oedema with syphilis
Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....
Orbital cellulitis outcomes for children
This paper discusses the clinical profile and multidisciplinary team (MDT) management outcomes in children treated for paediatric orbital cellulitis. This was a prospective study of 40 children with a mean age of 7.5 years (4-12). Unilateral orbital cellulitis cases had...
Clinical features of ocular syphilis
The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...
Orbital manifestations of granulomatosis with polyangitis
This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...
Nepafenac punctal plugs after cataract surgery: a new alternative?
The nepafenac punctal plug delivery system (N-PPDS) is an experimental L-shaped plug made of nonbiodegradable, preservative-free medical-grade silicone. It can deliver a sustained level of nepafenac for six weeks. This is a prospective, randomised, parallel-arm, double-masked, placebo-controlled, phase II pilot...
A novel way to distinguish between types of anterior ischaemic optic neuropathy
The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...
