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Orbital manifestations of granulomatosis with polyangitis

This a retrospective, observational study where authors looked at the ophthalmological examination, biopsy, antibodies and CT scan results of all patients diagnosed with granulomatosis with polyangitis (GPA) from January 2007-January 2019. Out of 101 patients with diagnosis of GPA, 15...

Nepafenac punctal plugs after cataract surgery: a new alternative?

The nepafenac punctal plug delivery system (N-PPDS) is an experimental L-shaped plug made of nonbiodegradable, preservative-free medical-grade silicone. It can deliver a sustained level of nepafenac for six weeks. This is a prospective, randomised, parallel-arm, double-masked, placebo-controlled, phase II pilot...

A novel way to distinguish between types of anterior ischaemic optic neuropathy

The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...

Profile of sympathetic ophthalmia (SO)

The authors undertook this study to examine the clinical profile of patients aged <18 years with SO over the past 20 years. This was a hospital-based retrospective study from 1997 to 2017. SO is a diagnosis of bilateral panuveitis following...

Migraine and risk of retinal artery occlusion

This retrospective cohort study assessed whether migraine was associated with an increased risk of retinal artery occlusion. They reviewed a large insurance database of 418,965 patients who suffered with migraines between 2007 and 2016. These were then matched with an...

Prevalence and incidence of uveitis

Uveitis encompasses a group of diseases characterised by the inflammation of fovea uvea which are potentially vision threatening. However, the frequency of this condition is unclear. This systematic review and meta-analysis aimed to provide estimates of the frequency of uveitis...

Evaluation of fluocinolone acetonide in the management of BRC

This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...

Presenting and diagnostic signs of retinoblastoma

This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...

Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis

This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....

Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review

Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...