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Advances and developments in medical retina

The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...

The Sickle Cell Retinopathy Network is leading global change in screening and management

Sickle cell disease or disorder (SCD) is one of the most neglected health conditions in the world. A strong hypothesis is that this is because SCD affects people of African, Caribbean and other Global Majority communities and has received disproportionately...

Seven in ten UK adults support compulsory eye tests for drivers to improve road safety, new research reveals

The College of Optometrists and the Association of Optometrists say research shows “current vision checks aren’t keeping pace with what’s needed to keep everyone safe on the road” Seven in ten UK adults support calls for the introduction of mandatory...

What's trending Apr/May 2024

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #GrahamNorton #eyelids Graham Norton’s chat show is always a must-watch in my book. I was particularly surprised to find two eye-related...

25 years of OCT

David Huang first described optical coherence tomography (OCT) in 1991, in his seminal paper on the subject in Science. This method developed the work of others on ophthalmic interferometry, which essentially showed that measuring reflected light could be used to...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

The lived experience of benign essential blepharospasm

Benign essential blepharospasm (BEB) is a rare neurological condition which causes involuntary sustained or intermittent muscular contraction of both eyelids and upper facial muscles which cause closure of eyelids, abnormal facial expressions and distress [1]. The term dystonia is an...

A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....

A randomised, controlled trial of oral propranolol in infantile haemangioma

Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...

Inhibiting high-risk corneal allografts

The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...

Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD

This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...

Atropine treatment for myopia in western countries – rationale

This preliminary study sets out the rationale, methodology and participant baseline characteristics for the Western Australia Atropine for the Treatment of Myopia (WA-ATOM). It is a double masked randomised placebo-controlled trial. This study is designed to be combined with the...