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Efficacy of BT as a treatment for cranial nerve palsy in acute and chronic cases

The authors performed a meta-analysis of all patients’ treatment with botulinum toxin (BT) for cranial nerve palsy (CNP) to determine the efficacy of BT in the treatment of CNP due to a variety of causes. The search identified 1129 articles...

Innovative 3D printing could revolutionise treatment for cataracts and other eye conditions

University of East Anglia researchers have made a significant breakthrough in ocular device technology with the introduction of a novel resin for 3D printing intraocular devices. This innovation has potential to enhance the manufacture of eye implants universally used in cataract and refractive surgeries.

East of Ealing

“And Cain said unto the Lord, my punishment is greater than I can bear. Behold, thou hast driven me out this day from the face of the earth; and from thy face shall I be hid. And Cain went out...

No such thing as a free lunch

Rudyard Kipling was a very wise chap. He was in San Francisco towards the end of the 19th century and noticed that in some bars and saloons the house was giving away free lunches for every patron who first purchased...

Randomisation, confounding & observational methods in ophthalmic epidemiology

Randomisation and confounding Understanding the relationship between an exposure and an outcome of interest is the central challenge in ophthalmic epidemiology. The exposure may be aetiological, taking the form of a putative risk biological factor, or therapeutic, in the form...

Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...

Herpes zoster ophthalmicus: a clinician’s perspective

Introduction Herpes zoster, commonly known as shingles, is caused by the reactivation of varicella zoster virus (VZV). The term herpes is derived from a Greek work, herpein, which means ‘creeping’ and the word zoster means a belt or a girdle...

ISD-DE (International Society of Dacryology and Dry Eye) Meeting 2024

by Jane Olver, FRCS FRCOphth, President ISD-DE and 2024 London Meeting Organiser, owner and Medical Director, Consultant Oculoplastic Surgeon, Clinica London. The International Society of Dacryology and Dry Eye (ISD-DE) 2024 update course and scientific meeting ran between 29, 30...

SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so

Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...

Apr/May 2019 Quiz

History A 68-year-old female patient was referred from her GP with bilateral conjunctival lesions on her upper eyelids which cause local irritation and dry eyes. Her past ophthalmic history is uneventful. However, systemically she has history of high blood pressure...

A practical guide to anisocoria

Anisocoria means the presence of difference in the size of the right and left pupils. It is a sign of an abnormality in the efferent pathway. The first question facing the ophthalmologist is to ascertain if anisocoria is present or...

Iris chafing from displaced single-piece acrylic IOL

A 74-year-old man had persistent 3+ cell one month following left eye cataract extraction, complicated by anterior capsular rent and zonular dialysis at 7 o’clock, with single-piece acrylic intraocular lens implantation (IOL) in the capsular bag. Figure 1: Haptic-like transillumination...