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PD-1 and PD-L1 in exenteration specimens
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
Laser speckle contrast imaging (LSCI) enables perfusion monitoring of the anterior segment during strabismus surgery: a study on the horizontal rectus muscles
Forty-four eyes with horizontal strabismus surgery involving medial and / or lateral rectus muscle detachment were recruited. The perfusion in the adjacent paralimbal and iris tissue was monitored with LSCI technique, by using a PeriCam PSI NR System. An infrared...
Cadaveric measurements of the Spiral of Tillaux
The authors conducted a cadaveric study to investigate and analyse the variability of the mean distances of the extra-ocular muscle insertion sites from the limbus as well as corneal diameters. The study included measurements taken from 30 white cavaders; 50%...
Quality and readability of online web information for childhood glaucoma
In this study, the quality, reliability, technical quality and readability of online information related to childhood glaucoma was assessed. This was a cross-sectional study of websites discussing childhood glaucoma. The authors undertook an analysis of 500 websites over a six-month...
Lester Jones tubes: Can these be tolerated long-term?
The authors present a retrospective case review study of a cohort of patients with Lester Jones’ tubes first placed between 1969 and 1989, and who were reviewed within the last 15 years. Twenty-nine patients (33 eyes) were included in the...
Long-term outcomes for hereditary retinoblastoma
Earlier diagnosis and more rigorous treatment regimens have contributed to better outcomes for patients with retinoblastoma. This study looked at 24 patients with hereditary bilateral retinoblastoma treated with systemic chemotherapy during a ten year period (2001-2011). The medical notes were...
Allergic conjunctivitis evaluation by thermography
Thermography is a non-invasive imaging technique, which uses infrared radiation reflected from an object to estimate the temperature of the object. This paper evaluates the use of thermography to assess allergic conjunctivitis objectively, by using an instrument called ocular surface...
Use of amniotic membrane in second stage Hughes tarsocunjunctival reconstruction
This is a retrospective, non-comparative interventional case series of 30 patients who underwent amniotic membrane transplantation to lower lid margin as part of Hughes lid reconstruction to prevent a hyperaemic, hypertrophic conjunctival margin with excessive discharge. Patients undergoing more than...
Radiotherapy for orbital apex cavernous haemangiomas
This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....
Delayed EPBRT efficacy in retinoblastoma
This is a retrospective medical records review of 50 patients (54 eyes) with retinoblastoma (RB), who received I-125 episcleral plaque brachytherapy (EPBRT) prior to (primary) or following chemoreduction (delayed) alone and in combination with non-irradiative focal therapy. Fifty-six plaques were...
Ocular adnexal marginal zone b-cell lymphoma
This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...
