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3566 results found

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...

Enzymatic clearance of anterior chamber infiltrate in uveitis

Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

South-South collaboration for the treatment of avoidable blindness in Botswana

This article describes the value of South-South collaboration in the reduction of avoidable blindness. Specifically it describes a South-South collaboration between India and Botswana that evolved out of the VISION 2020 LINK between Cambridge University Hospitals, two institutions in India...

Exotropia symptoms

The aim of this study was to evaluate clinical preoperative symptoms and changes to these postoperatively in patients with exotropia. A non-validated questionnaire with 15 questions was used: three subscales including stereopsis (five questions), ocular fatigue (five questions) and cosmetic...

GA vs. office measures of axial length

Axial lengths were compared in an office setting versus under general anaesthetic (GA) to determine if awake office measures are feasible and whether differences in measures occur in both settings. The study included 33 eyes of 19 children; 84% male,...

Iran prevalence of amblyopia

The authors aimed to determine the prevalence of amblyopia, its relation with refractive errors and its determinants. The target population was all children aged seven years in Iran. There were 3675 of 4157 children who participated (88.4%) with final analysis...

Role of fundus autofluorescence patterns and baseline atrophy area on geographic atrophy progression

Central geographic atrophy (GA) is one of the morphological sub types of late-stage macular degeneration. The natural course of the disease is characterised by expanding areas of macular atrophy, which cause absolute scotoma. Fundus autofluorescence (FAF) is derived from lipofuscin...

Patient-reported outcomes in oculoplastic surgery

This is an important if somewhat difficult to grasp article which tries to formally address the subject of patient-reported outcomes in oculofacial surgery. The authors have conducted an extensive review of the literature searching for instruments (questionnaires) which have been...

Visual defects in deaf children and young adults

This literature review article serves as a great update on the current evidence relating to visual defects in the young deaf population. There is a good introduction with background information and demographic data relating to UK hearing impairment. The authors...

Density of cataract and its influence on retinal nerve fibre layer thickness

The aim of this study was to further define and model the influence of cataract on spectral domain optical coherence tomography (SDOCT) image quality and retinal nerve fibre layer (RNFL) thickness measurements. OCT quality is influenced by opacities in the...

Long-term treatment of blepharospasm using Botulinum Toxin A

The authors report findings from a retrospective single-centre study which aimed to evaluate the efficacy and safety of long-term botulinum A toxin (BAT) treatment in patients with blepharospasm (BPS). Blepharospasm is described as one of the most frequent types of...

Transconjunctival eyelid weight insertion

This is a description of a new surgical technique to insert upper lid weights via a posterior, transconjunctival route. Following local anaesthetic, the upper lid was everted over a Desmarres retractor with a silk traction suture. A 5mm high central...