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How much money is wasted on tests prior to cataract surgery? And why?
For routine cataract surgery, numerous studies have found that preoperative testing does not contribute usefully to safety or surgical success. Despite such guidelines, tests ordered for patients prior to phacoemulsification in the US remains high. To quantify the associated costs,...
Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis
In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...
Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients
This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...
Beware the disc in myopic patients
Glaucoma is a chronic and progressive optic neuropathy characterised by damage of retinal ganglion cells. Evaluation of structural damage of the optic nerve is important in glaucoma diagnosis. The ISNT rule states that the neuroretinal rim width is generally widest...
Ginko bilboa extract affects hypoxic retinal pigment epithelial cells
Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...
A comparative evaluation of a new diffractive trifocal and EDOF IOLs
This study aimed to compare the outcomes of two diffractive trifocal intraocular lenses and one extended depth of focus (EDOF) intraocular lens (IOLs). This was a six month, single centred, prospective, randomised, comparative study in which patients who underwent routine...
Contrast sensitivity after laser corneal surgery
This study group compared contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimised photorefractive keratectomy (PRK) or laser-assisted in situ keratomileusis (LASIK) for the treatment of myopia or myopic astigmatism 12 months after surgery. This was a prospective, randomised clinical trial,...
Comparing femtosecond laser assisted-DMEK to manual DMEK
Femtosecond laser is as a novel tool for performing precise descemetorhexis in descemet membrane endothelial keratoplasty (DMEK) surgery. In DMEK surgery, the recipient’s Descemet membrane is peeled to allow adherence of the donor DMEK tissue to the recipient’s stroma. Complete...
Retinoschisis
In this retrospective study the authors evaluate the effect of pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling for lamellar macular hole (LMH) with or without macular retinoschisis in highly myopic eyes. Twenty-one highly myopic patients (22 eyes)...
Practice patterns of uveal melanoma management with Iodine-125 brachytherapy
With the 2006 Collaborative Ocular Melanoma Study Group (COMS) study demonstrating no difference in survival outcomes for participants randomised to either iodine-125 brachytherapy or enucleation, the majority of primary uveal melanomas in the United States are now treated with brachytherapy....
Undetected retinoblastoma management following vitrectomy
This retrospective study from a single-centre referral university hospital in Germany analysed data collected between 1991-2019 to comment on management and complications of undetected retinoblastoma eyes following vitrectomy. The 10 patients included had a mean age of 36.1 months (range...
