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Influence of FLEx and SMILE on corneal nerve density and ocular surface

This was a prospective study designed to compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on the corneal nerve density and ocular surface for myopic correction. Thirty patients underwent bilateral lenticule extraction. One eye...

PUK after corneal crosslinking

This retrospective study aimed to report the incidence, characteristics, clinical presentations, risk factors, and the available treatment modalities of sterile peripheral ulcerative keratitis (PUK) post-corneal collagen crosslinking (CXL). In total 771 eyes of 474 patients operated for keratoconus or ectasia...

Can intravitreal anti-VEGF injections affect corneal nerves?

This was a retrospective case-control study looking at the effect of anti-VEGF injections on corneal nerves (CN). Fifty-seven patients with a history of at least three anti-VEGF injections in one or both eyes and available confocal microscopic imaging were included...

Advances in the understanding, diagnostic and treatment of keratoconus

*Joint first authors Keratoconus is a bilateral and asymmetric eye condition in which the cornea’s structure is affected and thinned, causing a cone-shaped bulge to develop. This results in progressive loss of vision and impairs the ability of the eye...

How to diagnose and treat Acanthamoeba keratitis

Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

HS-UK to host ‘Beat the President’ competition at the UKISCRS Annual Congress

HS-UK are pleased to be exhibiting at the 47th UKISCRS Annual Congress at the Leonardo City Hotel, on Thursday 2nd & Friday 3rd November, 2023.

Use of the Mendonca strabismus forceps in locating and measuring muscle insertions

The authors aimed to compare the reliability of the Mendonca strabismus forceps vs intraoperative calliper measurements for determining the distance from the limbus to the insertion of the extraocular muscles in patients undergoing strabismus surgery. This was a prospective observation...

Apr/May 2017 Quiz

History A five-month-old baby was seen in clinic with bilateral congenital corneal opacities. The right cornea is shown in Figure 1. Figure 1. Examination revealed corneal oedema and opacities of Descemet’s membrane and endothelium with a few vesicular lesions. Corneal...

In vivo confocal microscopy, principles and use in keratitis Part 1: Principles

In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....

Presumed DALK stromal graft rejection following Covid-19 infection

Case report A 45-year-old healthy male patient with a past ocular history of keratoconus and right deep-anterior lamellar keratoplasty (DALK) graft performed 10 months prior, presented to our eye casualty clinic with a two-day history of right photophobia and epiphora....

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

175 years of Ernst Fuchs: The man behind the eponyms

14 June 2026 marked 175 years since the birth of Professor Ernst Fuchs: a teacher, writer, pathologist and one of the great founders of modern ophthalmology, whose name echoes through clinics, exams and theatres worldwide to this day. Most doctors...