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2326 results found

Congenital nasolacrimal duct obstruction in patients with craniofacial abnormalities

This is a retrospective study including 1998 patients over a period of 10 years. Of this number, 41 patients were identified as having a craniofacial abnormality and congenital nasolacrimal duct obstruction (CNLDO) (23.1 per 10,000 live births). Interestingly the most...

FSAK versus toric IOL implantation for correcting astigmatism in cataract patients

Nine studies of 590 patients were retrieved from the Ovid-Medline, EMBASE, Cochrane register of controlled trials and Scopus which compared femtosecond laser-assisted astigmatic keratotomy (FSAK) and toric IOL for astigmatism correction in cataract patients. The trial sequential analysis was used...

Reporting the development and pilot use of fixable surgical instruments

This study reports the development of instruments to substitute traction sutures during strabismus surgery and to act in place of surgical assistance. Three types of instruments were developed: (1) fixable multi-functional forceps; (2) fixable muscle hook; and (3) fixable retractor....

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Codifying ‘care’ and ‘cure’ behaviours of artificial intelligence systems: now out in Nature Medicine

A new publication in Nature Medicine discusses 'Building a code of conduct for AI-driven clinical consultations' The diversity of AI applications in medicine is growing at an accelerating rate, with that trend set to continue as technology develops. This diversity...

AI glaucoma screening cost-effective in the Netherlands?

Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...

Keratoconus prevalence in astigmatic adolescents

The authors from Israel performed a cross-sectional study of 896,377 adolescents aged 16–20 years who underwent refraction and topography/tomography between 2011 and 2022. A total of 1886 (0.21%) were diagnosed with keratoconus with increasing astigmatism level being strongly associated with...

Biomarkers in thyroid eye disease

An ideal biomarker is sensitive, specific, easily assessable and clinically relevant. This study looked at the presence of inflammatory cytokines present in the tear film of healthy controls, thyroid patients without eye disease (non-TED) and those with thyroid eye disease...

Use of reduced volume BT as a treatment option for acute onset comitant esotropia

In this study, the effectiveness and safety of botulinum toxin (BT) for patients with acute acquired comitant esotropia (AACE) and deviation ≤25PD was investigated with comparison of results to conservative prism therapy. Botulinum toxin was undertaken without electromyographic guidance and...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

Strengthening diabetic retinopathy services in Nigeria through DR-NET – from grass roots to national policy development

This is the third article in a series (see Part 1 and Part 2) reflecting on how shared learning via networks of UK and international eye health professionals is contributing to reducing unnecessary blindness in Nigeria. Earlier articles focused on...