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The compendium to clinical evidence in DMO treatment

This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these...

Review of chalazion treatment

Even though chalazion is a common eyelid lesion, there is lack of consensus on a treatment algorithm. Conservative management includes lid hygiene and warm compresses and, in some cases, steroid ointments for two to three weeks. More invasive options for...

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

Use of Leflunomide as a treatment for paediatric chronic uveitis

Leflunomide is a disease modifying anti-rheumatic drug approved for treatment of rheumatoid arthritis and psoriatic arthritis in adult patients. This study reports five illustrative case reports of children using Leflunomide as an adjunct treatment with anti-tumour necrosis factor (TNF) agents...

Low-dose atropine 0.01% for the treatment of childhood myopia: a pan-India multicentric retrospective study

This is a retrospective multicentre study (20 centres) in India over two years, monitoring the progression of myopia after starting treatment with 0.01% atropine drops. Seven-hundred and thirty-two children were recruited in the study, between six and 14 years old,...

Repeat corneal collagen cross-linking after failure of primary cross-linking (CXL) in keratoconus

This is a 10-year, retrospective, patients record review from Leeds, UK. Twenty-one eyes had repeated CXL and the mean interval between primary and repeat CXL was 47.1 months. Twenty (95%) eyes stabilised after repeated CXL at a mean follow-up of...

Treatment for chronic severe bilateral blepharokeratoconjunctivitis

This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...

Inferior oblique botulinum toxin as a postoperative test

The authors aimed to evaluate the role of inferior oblique (IO) botulinum toxin (BT) injection as a surgical simulator prior to IO myectomy, i.e. preoperative diplopia test using BT. This was a retrospective review in a single centre over a...

BTA as a first-line treatment option for acute acquired comitant esotropia

This study presents results of a single-centre institute use of botulinum toxin A (BTA) as an initial treatment choice for acute acquired comitant esotropia (AACE). This was a prospective observational case series study of 72 patients (49 male, 23 female)...

BT as an effective alternative treatment for small angle consecutive exotropia

In this study, the authors evaluate the efficacy of botulinum toxin A (BTA) as a treatment option for consecutive exotropia. This was a retrospective review of 34 patients; 23 female and 11 male. Age at BTA was a mean of...

Use of reduced volume BT as a treatment option for acute onset comitant esotropia

In this study, the effectiveness and safety of botulinum toxin (BT) for patients with acute acquired comitant esotropia (AACE) and deviation ≤25PD was investigated with comparison of results to conservative prism therapy. Botulinum toxin was undertaken without electromyographic guidance and...