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2873 results found

Risk of pulled-in-two syndrome

Congenital fibrosis of the extraocular muscles (CFEOM) is along the risk factors for pulled-in-two syndrome (PITS). The aim of this study was to report six cases and discuss prevention and clinical management strategies. The author’s six cases represented an incidence...

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

Augmented surgery with BTA for large angle strabismus correction

This retrospective study reports the results of botulinum toxin A (BTA) augmented bilateral recession or monocular recession / resection (RR) for patients with large angle strabismus. Twenty-four patients were recruited: 10 female, mean age 9.2 ±13.6 years, 20 esotropia and...

Identifying life-threatening uveal melanoma: A directed application of general-purpose AI

Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...

Modern trabeculectomy outcomes

This audit was conducted by the Trabeculectomy Outcomes Group Audit Study Group to report on the efficacy and safety of current trabeculectomy surgery in the UK. This is relevant in light of the fact that the trabeculectomy outcomes presented by...

See sweet to C-suite: Carrie MacEwen

The business world tells us, “Know your why.” But increasingly, we live in a society where people think, “Why bother?” In this interview, David wants to know what makes Carrie MacEwen tick, and why she bothered to get involved locally,...

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

Ophthalmology in the developing world

After the second year of medical school, I spent my summer vacation working as a volunteer for a small Italian non-government organisation (NGO), named HEALTH-AID. As part of my volunteering experience, I joined a team of European doctors, medical students...

Treatment for cause of sudden sight loss now available through the NHS in England

The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

NICE approves treatment for cause of sudden sight loss

The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

Apr/May 2018 Quiz

History A 57-year-old lady presents with a right subconjunctival lesion which has been increasing in size for three months (Figure 1). She has never had vision problems other than presbyopia. Past medical history: hypertension and asthma. On examination, she had...