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Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

Ethnic variation in strabismus patterns in Down syndrome

The authors present a systematic review and meta-analysis evaluating the prevalence and aetiology of strabismus in individuals with Down syndrome, with particular focus on ethnic variation in the esotropia to exotropia ratio. Data from multiple studies across diverse populations were...

Improving reading of fundus photographs in an emergency setting

The first phases of the FOTO-ED study found that emergency providers perform significantly better with fundus photography than with direct ophthalmoscopy in the detection of fundus abnormalities. The authors hypothesised that by providing additional training to emergency providers, this would...

Identifying life-threatening uveal melanoma: A directed application of general-purpose AI

Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...

Pharma chameleon

One morning in September ’95, about a month into my first house job on the South Coast of England, I emerged from the ridiculously early ward round on the coronary care unit feeling a bit dazed and therefore headed off...

Specsavers joins IAPB to advocate for better eye health

The International Agency for the Prevention of Blindness (IAPB) proudly welcomes Specsavers as a pivotal new member, joining the global alliance for the eye health sector in the fight against avoidable sight loss. "For more than four decades, Specsavers has...

Recommendation for wide angle fluorescein angiography to diagnose FEVR in NEDSDV

Neurodevelopmental disorder with spastic diplegia and visual defects (NEDSDV) is a genetic disease described in 2012 associated with variants in the CTNNB1 gene which encodes beta-catenin. Characteristics include strabismus, reduced visual acuity and familial exudative retinopathy (FEVR). In this study,...

In conversation with Professor Bernie Chang, President, Royal College of Ophthalmologists

Congratulations on your appointment as RCOphth President in May last year. COVID-19 hit just before your presidency started. This must have been an incredibly challenging time to take the reins. How has the College risen to the challenges? Thank you....

The meaning of life

Supercomputer: “The answer to the great question of Life, the Universe and Everything is…”Programmer: “Yes…?”Supercomputer: “42. It was a tough assignment”.Programmer: “42? Is that all you have got to show for seven and a half million years work?” In this...

Is it NAION… Now what?

Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

Long way up

In the first of a series of guest editorials exploring multiple different Learning Curves, Francis Sanders ruminates on motorcycling and environmental guilt. As an avid motorcyclist, I was naturally drawn to the relatively recent sequel series from Ewan McGregor and...

How to be a better optometrist – a personal view

Our optometry editor shares her personal observations of what makes the best optometrist. Some years ago in Glasgow, I gave a presentation with this same title, ‘How to be a better optometrist’. I was the optometry programme director for NHS...