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Long-term effect of gene therapy on Leber’s congenital amaurosis

1 October 2015 | | EYE - Vitreo-Retinal
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

Sutureless, scleral fixated-IOLs

1 April 2020 | | EYE - Cataract, EYE - Refractive
This was a retrospective cohort study of 112 sutureless, scleral-fixated posterior chamber intraocular lens implantations (SSFCIOL) over a four-year time period. Mean follow-up duration was 13.0 ±10.4 months. The primary indication for SSFCIOL was dislocation of IOL due to zonular...
Case Reports in Ophthalmology journal cover image

Unique case of steroid-induced intraocular pressure spike causing NAION

7 April 2021 | | EYE - Neuro-ophthalmology | Herpes zoster, Intraocular pressure, Ischemic optic neuropathy, NAION
The literature describes previous cases of nonarteritic anterior ischaemic optic neuropathy (NAION) following rapid rises in intraocular pressure (IOP) leading to reduced optic nerve head perfusion and disruption. This is commonly following ophthalmic procedures, acute glaucoma or steroid eye drops....

Twenty-five years in retina

1 February 2019 | | EYE - Vitreo-Retinal, EYE - General
In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...

Toxoplasmosis and the associated retinochoroiditis: important facts and when to treat

1 April 2017 | | EYE - Vitreo-Retinal
Annie SeeWah Tung provides an overview of toxoplasmosis retinochoroiditis, including guidance on which cases should be treated and the treatment options. Toxoplasmosis retinochoroiditis is an infectious condition that is characterised by retinochoroidal lesions commonly in the posterior pole and is...

Progress in retinal disease management: Highlights of the Retina Day, RCOphth 2025 Annual Congress

4 August 2025 | | EYE - Vitreo-Retinal
The Retina Day meeting at the Royal College of Ophthalmologists (RCOphth) 2025 Annual Congress in Liverpool was held on 22 May 2025. This report highlights 10 selected topics of interest to subspecialists and general ophthalmologists. Decarbonising anti-VEGF clinics (or making...

Ocular manifestations of multiple sclerosis: an overview

1 December 2022 | | EYE - Neuro-ophthalmology, EYE - Pathology
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

The ophthalmologist’s elbow: a potentially painful point of contact

1 February 2015 | | EYE - General
Three months ago I leant, in the customary manner, on the box of my indirect lens at the slit lamp to examine a patient’s fundus. An acute and severe pain in the tip of my elbow immediately interrupted me. I...

Photophobia: an unusual symptom of a pituitary macroadenoma

2 February 2024 | | EYE - General
Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...

A log in the eye

1 February 2017 | | EYE - Vitreo-Retinal
"My friend wanted to show how far he could throw that log. So, he helicoptered it over his head, faster and faster and when he let go, it hit my eye at full speed,” a young lady of 19 years...

Exploiting nature’s randomised trials of eye disease

1 December 2022 | | EYE - Glaucoma, EYE - Vitreo-Retinal, EYE - Orbit
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

2019 ICO-Allergan Research Fellowship awarded

4 July 2019
Dr Matias Iglicki, from the University of Buenos Aires in Argentina, has been selected as the second recipient of the International Council of Ophthalmology (ICO)-Allergan Fellowship Award, by a panel of leading experts.