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Paraproteinaemia: a patient with atypical corneal findings

1 December 2013 | | EYE - Cornea, EYE - General
A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa [1]. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström’s macroglobulinemia. Multiple...

Corneal Topography in Clinical Practice (Pentacam System)

1 February 2014 | | EYE - Imaging, EYE - Cornea, EYE - General
This book is based upon one device, the Pentacam, developed by OCULUS, and is primarily aimed at those who wish to familiarise themselves with the Pentacam system and need a text to complement the instrument operations manual. It is laid...

Influence of FLEx and SMILE on corneal nerve density and ocular surface

1 August 2015 | | EYE - Cataract, EYE - Refractive
This was a prospective study designed to compare the influence of femtosecond lenticule extraction (FLEx) and small incision lenticule extraction (SMILE) on the corneal nerve density and ocular surface for myopic correction. Thirty patients underwent bilateral lenticule extraction. One eye...

PUK after corneal crosslinking

1 April 2019 | | EYE - Cornea, EYE - General
This retrospective study aimed to report the incidence, characteristics, clinical presentations, risk factors, and the available treatment modalities of sterile peripheral ulcerative keratitis (PUK) post-corneal collagen crosslinking (CXL). In total 771 eyes of 474 patients operated for keratoconus or ectasia...

Can intravitreal anti-VEGF injections affect corneal nerves?

1 June 2019 | | EYE - Cornea, EYE - General
This was a retrospective case-control study looking at the effect of anti-VEGF injections on corneal nerves (CN). Fifty-seven patients with a history of at least three anti-VEGF injections in one or both eyes and available confocal microscopic imaging were included...

Advances in the understanding, diagnostic and treatment of keratoconus

1 December 2022 | | EYE - General
*Joint first authors Keratoconus is a bilateral and asymmetric eye condition in which the cornea’s structure is affected and thinned, causing a cone-shaped bulge to develop. This results in progressive loss of vision and impairs the ability of the eye...

How to diagnose and treat Acanthamoeba keratitis

1 February 2019 | | EYE - Cornea, EYE - General
Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

HS-UK to host ‘Beat the President’ competition at the UKISCRS Annual Congress

20 September 2023 | Awards, Conferences & Anniversaries
HS-UK are pleased to be exhibiting at the 47th UKISCRS Annual Congress at the Leonardo City Hotel, on Thursday 2nd & Friday 3rd November, 2023.

Apr/May 2017 Quiz

1 April 2017 | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A five-month-old baby was seen in clinic with bilateral congenital corneal opacities. The right cornea is shown in Figure 1. Figure 1. Examination revealed corneal oedema and opacities of Descemet’s membrane and endothelium with a few vesicular lesions. Corneal...

In vivo confocal microscopy, principles and use in keratitis Part 1: Principles

1 April 2018 | | EYE - Cornea, EYE - Imaging
In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

1 October 2014 | | EYE - Cornea
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Presumed DALK stromal graft rejection following Covid-19 infection

4 December 2024 | | EYE - Cornea
Case report A 45-year-old healthy male patient with a past ocular history of keratoconus and right deep-anterior lamellar keratoplasty (DALK) graft performed 10 months prior, presented to our eye casualty clinic with a two-day history of right photophobia and epiphora....