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Identifying life-threatening uveal melanoma: A directed application of general-purpose AI

Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...

Semaglutide and vision loss: A new concern for NAION risk?

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as transformative agents in...

Ultra-widefield imaging in glaucoma: Documenting hypotony-related choroidal effusions after microshunt surgery

Ultra-widefield (UWF) imaging provides extended visualisation of the posterior segment beyond the traditional 30–50° field of view. It captures a broad view of the posterior pole and periphery in a single, quick, non-mydriatic acquisition. While its role in diabetic retinopathy...

Ophthalmic entrepreneurship: Reflections from an ophthalmic surgeon

For many ophthalmic trainees and newly appointed consultants, the idea of medical entrepreneurship can feel distant and sometimes uncomfortable. We are trained in a profession centred on patient care, ethics and service. The word entrepreneur, by contrast, often brings to...

The role of artificial intelligence in cataract surgery: An overview

Cataracts are still a leading cause of blindness and, with an ageing population, that burden will only grow [1]. Increasingly experts are leaning on technology such as ‘Surgery 4.0’ [2] – where smart machines and artificial intelligence (AI) slide into...

Ocular surface special: Ocular manifestations of Stevens-Johnson syndrome

Stevens–Johnson syndrome (SJS) is an uncommon dermatological emergency on the same clinical spectrum as toxic epidermal necrolysis (TEN). SJS is characterised by an acute, immune-mediated attack on the skin and mucous membranes, producing a rapidly progressive erythematous eruption with blistering...

Ciclosporin and dry eye

Dry eye has an estimated prevalence of between 5 and 50% worldwide and has physical, psychological and socioeconomic consequences for the human population [1]. Loss of tear film homeostasis with associated ocular surface inflammation causes symptoms ranging from ‘tired’ eyes...

Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform

The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...

The extended role of the specialist ophthalmic photographer

The prevalence of certain retinal conditions such as diabetic retinopathy and age-related macular degeneration (ARMD) is projected to grow substantially over the next decades. Estimates for the projected growth in burden on eye services for diabetic retinopathy and neovascular ARMD...