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My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

The meaning of life

Supercomputer: “The answer to the great question of Life, the Universe and Everything is…”Programmer: “Yes…?”Supercomputer: “42. It was a tough assignment”.Programmer: “42? Is that all you have got to show for seven and a half million years work?” In this...

The ghost of Christmas present

“Ah, youth is wasted on the wrong people.” Some will recognise this as one of the many brilliant quotes from what is considered to be the best Christmas movie ever – Frank Capra’s tear-jerker It’s a Wonderful Life (1946), although...

Congenital cataract

Congenital cataract is the clouding or opacification of the lens that occurs at birth or weeks after (infantile cataract). They can be unilateral or bilateral and vary in form, size and location, and consequently the visual impact, management course and...

Tricks and tips for paediatric refraction

Refraction is an important part of the paediatric eye examination but can sometimes be challenging. If a child struggles to co-operate with the eye examination, how can one ensure that the best outcome is achieved? There are tips here which...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Beyond vision loss: Why doctors should know about Charles Bonnet Syndrome

Over 250 years have passed since Charles Bonnet’s seminal essay, in which he described the symptoms of the syndrome that now takes his name [1]. Charles Bonnet Syndrome (CBS) describes the occurrence of visual hallucinations in people with significant visual...

Working smarter not harder: How to transform eyecare delivery in the United Kingdom (part 1)

Are we doing enough to meet the current demands on ophthalmic services? In part one of a two-part series (see Part 2 here), Rosalind Harrison takes a look at how efficiency has been improved in eyecare services in the US....

Guildford Rotary Eye Project

Guildford Rotary Eye Project (GREP) was conceived and implemented during the last 15 years with the sole aim to motivate and empower host Rotary clubs in India and Africa to resolve their problems with their own money. International partners in...

Blurred vision post liver transplant: to blame the house cat or not?

This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...

Advanced level practice for ophthalmic nursing

The Royal College of Nursing (RCN) Ophthalmic Nursing Forum (ONF) is committed to clinical excellence through advancing ophthalmic nursing practice and supporting career development. With the increasing demand for ophthalmic services, advanced and specialist practice roles are vital to increase...

White dot syndromes

It is fair to say that trainees and consultants who are not medical retina specialists are a bit scared of the so called retinal ‘white dot syndromes’. It is easy to understand why this is the case, as almost every...