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2866 results found

AMD and visceral fat and pro-inflammatory factors

Several large studies have shown a positive relationship between age-related macular degeneration (ARMD) and high body mass index. The waist-hip ratio is also associated with development of early AMD. Visceral fat has a pro-inflammatory effect, which means it has an...

Allografts in limbal stem cell deficiency

This prospective comparative study compared outcomes of live related limbal allograft (Lr-CLAL) versus cadaveric keratolimbal allograft (KLAL) in limbal stem cell deficiency secondary to ocular burns. Twenty patients were randomly allocated into each group. The Lr-CLAL group had a significant...

Structural effects of migraine on the retina

Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...

Reproducible OCT RNFL map in unilateral glaucoma

The aim of the study was to compare the reproducibility of the optical coherence tomography retinal nerve fibre layer (OCT RNFL) thickness map between glaucomatous and fellow normal eyes of unilateral glaucoma patients. The authors carried out a prospective case...

Do operative interventions for IIH improve visual function?

The authors of this paper reviewed patient case notes to determine visual outcome following shunt surgery for idiopathic intracranial hypertension (IIH). A retrospective case notes review was conducted for 50 patients who underwent shunt surgery for IIH. Outcome measures included...

Cost-effectiveness of femtosecond cataract surgery

Femtosecond laser-assisted cataract surgery has become increasingly popular due to the reported benefits of increasing precision and reproducibility of capsulorrhexis, less power and manipulation required during phacoemulsification, better corneal wound architecture, and the ability to place precise arcuate keratotomy incisions...

Arterial stiffness and PEX

The authors describe a study of 25 newly diagnosed patients with pseudoexfoliation glaucoma (PEX) and 25 controls to evaluate carotid femoral pulse wave velocity (CF-PWV) values. The CF-PWV was assessed using a noninvasive device by measuring the pulse transmit time...

Two bifocals and a trifocal

The authors compare the optical outcomes of two bifocal intraocular lenses (AcrySof ReSTOR +2.50 Diopter [D] add +3.0D add) with a trifocal lens (AT LISA tri 839MP). The optical qualities of the lenses were quantified by measuring the modulation transfer...

Ocular characteristics in Marfan syndrome

Marfan syndrome (MFS) is a genetic disorder with clinical manifestations associated with cardiovascular, ocular and skeletal organ systems. Typical signs are descending aortic root aneurysms, ectopia lentis, tall stature and scoliosis. This observational study looked at the ocular characteristics, visual...

Corneal biomechanics and refractive outcomes after cataract surgery

The authors aimed to study a range of corneal properties and correlate them with refractive outcomes after phacoemulsification. Outcomes were reviewed in a fairly small group of 40 patients (including only right eyes) operated by two surgeons using clear corneal...

Tear production levels and dry eye disease

Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...

IINS function

This study explored the impact of idiopathic infantile nystagmus syndrome (IINS) on quality of life in adults measured using the VFQ25 questionnaire. Of 38 subjects, 35 completed the questionnaire. Mean age was 35.1±13.0 years; 15 were British Caucasian and 14...