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Fenofibrate and diabetic retinopathy
Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...
Screening with PlusoptiX
This study compared the PlusoptiX A12 to a comprehensive ophthalmic investigation. This was a three-month study of 219 (438 eyes) subjects with a mean age of 72 months. The A12 referred 101 of 219 (46%) patients for potential amblyopia. Ophthalmic...
Driving with the use of spectacle mounted telescopes (bioptics)
The authors discuss the current perspectives of spectacle mounted telescopes (bioptics) whilst driving among patients with visual impairment. The history, design and driving laws surrounding the use of bioptics is discussed in detail. In 1977, William Feinbloom developed a bioptic...
Effect of caffeine and low intensity endurance exercise on intraocular pressure
This placebo controlled, double blind, balanced crossover study reports in healthy individuals that 30 minutes of cycling caused a maximum of 2.7mmHg lowering of IOP. A caffeine dose of 4mg/kg 30 minutes prior to cycling negated this effect. The conclusion...
Vision screening and socio-demographic disparities in Iranian school entrants
The authors present a large population-based cross-sectional study evaluating the vision status of children entering school in Iran and its association with socio-demographic characteristics. Parents reported whether their children had healthy vision, wore eyeglasses, or had suspected vision problems, alongside...
Evaluation of keratometry with a novel colour LED corneal topographer
The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...Myasthenia gravis presenting with isolated ptosis: a poorly studied subgroup
Investigation into the cause of one isolated symptom or sign can be challenging if that particular sign may be caused by a variety of pathological processes, affecting different tissues, and presenting to different specialties. Unilateral ptosis is a case in...
