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Medical treatment of orbital lymphatic malformations
This is a literature review of the use of Sirolimus, to treat orbital lymphatic malformations. Sirolimus is an immunosuppressant used in renal transplants, and acts by inhibiting mammalian target of rapamycin (mTOR), which in turn inhibits activation of T and...
How does low-concentration atropine reduce progression of myopia?
This is a double-blind, randomised, placebo-controlled trial evaluating the effects of low-concentration atropine (0.05%, 0.025%, 0.01%) on ocular biometrics of myopic children. The aim is to determine what aspect of ocular biometrics low-concentration atropine influenced in reducing the progression of...
Myopia progression with atropine and different treatment lenses
This study aimed to determine the effectiveness of low dose atropine at inhibiting myopia progression, the possible additive potency of this treatment combined with either of two peripheral defocus contact lenses over three years of therapy, and whether there was...
Profile of presentation, follow-up and management of orbital myositis
This retrospective study reviewed the demographic characteristics of patients with orbital myositis, their clinical profile, management options, outcomes and predictive factors for recurrence. The study included 52 patients (55 eyes; 3% bilateral involvement), 36 females, with mean age at presentation...Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
Comparison of in-person and telephone appointments for week 1 postoperative follow-up
This study evaluated engagement with a postoperative week-1 follow-up phone call, assessing safety, cost and travel savings. Electronic medical records of children (<18 years) having undergone strabismus surgery with a single surgeon during a 4-year period, were reviewed. Patients were...Home Wi-Fi / range and security tips
This issue covers two topics that relate to Wi-Fi. The first is keeping your wireless network secure and the second is extending its range. Keeping home Wi-Fi secure Let’s say the recent computer attacks that resulted in disruption to NHS...An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...Optical coherence tomography – reinventing the eye examination
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...
Intraoperative floppy iris syndrome and prevalence of intraoperative complications
Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...
A review of chromosome 9p21 POAG susceptibility locus
Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...
