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Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

ICG TTT for retinoblastoma

Transpupillary thermotherapy (TTT) is a specific form of ocular TT using infrared radiation (diode laser). Indocyanine green (ICG) is also used to achieve the optimal phototherapy effect in eyes with minimal pigment. Twenty-one patients with 42 retinoblastomas in 30 eyes...

Ranibizumab versus laser in diabetic macular oedema (LUCIDATE study)

The aim of this study was to compare the functional and structural effects of Ranibizumab versus macular laser treatment in patients with diabetic macular oedema. It was a single centre, prospective, randomised, single masked clinical trial spanning a 48 week...

Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification

This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...

Four year outcomes of macular degeneration treated with ranibizumab

The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...

Type 3 CNV and anti-VEGF

The purpose of the study was to determine the differences between aflibercept and ranibizumab in terms of their therapeutic efficacy in the treatment of Type 3 neovascularisation. The authors highlight that the dominant mechanism for Type 3 neovascularisation development is...

Comparison between findings in OCTA and FA in patients with diabetic retinopathy

In this study the authors present a prospective cross-sectional comparative study of typical findings of diabetic retinopathy to analyse the agreement between the image modalities of optical coherence tomography angiography (OCTA) and fluorescein angiography (FA). Fifty-three eyes of 42 patients...

RPE tears in cases of IPCV

The aim of this study was to investigate the occurrence, characteristics, management and prognosis of retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy (PCV). Medical records of previous cases were reviewed over an eight-year period from a...

OCT prognostic factors in AMD patients with peripapillary choroidal neovascularisation

In this retrospective study the authors aimed to investigate the correlation between optical coherence tomography (OCT) findings and visual acuity outcomes after treatment with intravitreal bevacizumab (IVB) injections for age-related macular degeneration (AMD) patients with peripapillary choroidal neovascularisation (PPCNV). Data...

The use of adalimumab for relapse in patients with Vogt-Koyanagi-Harada disease

In this retrospective, multi-centre, cohort study, the efficacy and safety of Adalimumab (ADA) treatment for the exacerbation or recurrence of Vogt-Koyanagi-Harada (VKH) patients was assessed by investigating the medical records of patients who had received ADA treatment for more than...

Comparison of paediatric migraine and healthy controls using optical coherence tomography angiography

The authors present a cross-sectional study which recruited patients with paediatric migraine without aura along with age and sex-matched healthy controls. Both groups were recruited following attendance to an ophthalmology outpatient clinic. Children diagnosed with any of the following were...

Normative data using a virtual reality game-based visual field test

The authors present a prospective cross-sectional study involving healthy children to assess the use of a virtual reality game-based perimetry assessment. A single eye centre recruited through paediatric optometry and ophthalmology clinics over a 12-month period. Children aged <18 years...