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PAX6 methylation and myopia

The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...

High myopia macular thickness

The purpose of this study was to compare macular thickness and volume in 15 highly myopic (>-6D) young children with 11 age-matched controls (-2 to +4D refractive errors) using Stratus third generation OCT. Mean spherical equivalent was -9.42 ±2.81D for...

Use of orthoK for myopia treatment

This article provides an updated literature review on the orthkeratology effect on myopia progression considering outcome measures, potential effect modifiers, mechanisms and current prescription concerns. The discussion centres on the extent of slowed myopia progression, mechanisms, safety concerns and comparisons...

LASIK for myopia progression

The authors hypothesise that corneal reshaping with refractive surgery could have an effect on myopic progression similar to that of orthokeratology because it results in changes to the central cornea and not to the peripheral cornea. This was a retrospective...

Effect of pregnancy on myopia

The authors present a longitudinal study with a large sample size assessing the association between pregnancy and the onset or progression of myopia. The study participants included the SUN cohort which comprised of young adult female university graduates in Spain....

Myopia in Han Chinese

The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...

Reducing myopia progression

This paper reports a literature review to discuss the environmental considerations and treatment options that can prevent the progression of myopia, including time spent outdoors, reduction of near vision activities, spectacle types, contact lens type and pharmacological treatment. The review...

Strabismus in high myopia

The authors report the occurrence of exotropia-hypotropia complex in 15 cases of high myopia. The mean age at presentation was 23.5 years (10-35 years). Only two patients had high bilateral myopia. The mean axial length of the deviating eye was...

Myopia-protective against diabetic retinopathy

This meta-analysis evaluates the current evidence of the relationship between myopia and diabetic retinopathy (DR) risk. A systematic search was performed up to April 2015. Three models were used to assess the association between myopia and risk of DR: axial...