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New mouse model of diabetes mellitus
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...
Association between diabetes mellitus and dry eye disease
Diabetes mellitus (DM) is currently one of the most prevalent chronic diseases in the United States. It is estimated that 12.3% of Americans suffer from DM. In this study the authors compare between dry eye and diabetes mellitus among a...Cataract incidence rates in patients from the UK suffering with diabetes mellitus
The authors summarise the main findings from a recent study which investigated the incidence rates of cataract in patients with or without diabetes mellitus (DM). Background to the study Worldwide, the World Health Organization (WHO) estimates that 253 million people...
Correlation between aqueous flare and macular microvascular status in diabetes mellitus
The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...
Systemic and Ophthalmic Management of Diabetes Mellitus
Chris Steele, the Head of Optometry in Sunderland Eye Infirmary, has a wealth of experience and knowledge in retinal pathology and has recently published what is now his second book on diabetes. This has been a major undertaking, taking three...Sustainable prevention of blindness from diabetic retinopathy through prevention and control of diabetes mellitus – LINK partnership experience in Dominica
The Caribbean Diabetic Retinopathy Project (DR Caribbean) is a five-year project that aims to reduce blindness due to diabetic retinopathy (DR) across four Commonwealth countries: Belize, Dominica, Jamaica and St Lucia. The VISION 2020 LINKS Programme at the London School...
Risks factors for graft preparation failure in DMEK
Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...
Diabetic retinopathy and body fat distribution and adipokine secretion in type 2 diabetics
The major risk factors for diabetic retinopathy (DR) in patients with diabetes are poor glycaemic or blood pressure control, duration of diabetes and nephropathy related to the severity of DR. Several studies suggest that DR is associated with visceral fat...
Evaluation of the association between diabetes autoantibodies and development of early diabetic retinopathy in type 1 diabetes
This study was conducted to investigate the relationship between diabetes autoantibodies and the development of early diabetic retinopathy (DR) to assess the role of autoimmunity in retinopathy. The study included 18 boys and 44 girls with type 1 diabetes mellitus...Strengthening diabetic retinopathy services in Nigeria through DR-NET – from grass roots to national policy development
This is the third article in a series (see Part 1 and Part 2) reflecting on how shared learning via networks of UK and international eye health professionals is contributing to reducing unnecessary blindness in Nigeria. Earlier articles focused on...
Risk factors for non-arteritic ischaemic optic neuropathy in an Asian population
The authors reviewed the medical records of 45 Korean patients with non-arteritic anterior ischaemic optic neuropathy (NAION) and 45 healthy controls, in order to determine risk factors for the condition in an Asian population. Previous studies looking at risk factors...
