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Diagnostic accuracy of different keratoconus detection indices of pentacam in paediatric eyes

This is a retrospective study of 432 non-keratoconic eyes compared with 48 eyes with keratoconus (KC) or forme fruste KC (FFKC) in a paediatric population in Cairo, Egypt between December 2013 and October 2018. The authors discuss the rationale of...

What about the children? Cornea cross-linking for children with keratoconus

Keratoconus can behave more aggressively in paediatric than in adult patients. Collagen cross-linking has been shown to slow the progression of keratoconus in adults. This systematic review determined the effectiveness of corneal collagen cross-linking (CXL) in children. For this study,...

Topography based keratoconus progression after corneal collagen cross-linking

Case 1 describes a 35-year-old man with progressive keratoconus (PK). His best corrected visual acuity (BCVA) was right 20/80 (-5.25/-7.75 x 85) and left 20/20 (+4.75/-5.00 x 90). His Ks were right 36.32/48.02 D and 41.15/46.41 D. Right central cornea...

Does cornea cross-linkage reduce the rate of corneal transplants in keratoconus?

Cornea cross-linking (CXL) is a relatively new treatment in the management of keratoconus, which may help prevent the need for corneal transplant. This paper investigates if the introduction of corneal cross-linkage has reduced the number of corneal transplants performed annually...

Effect of long-term RGP-CL wear on keratoconus progression

This is a retrospective study between April and December 2017, of 22 rigid gas-permeable contact lens (RGP-CL) patients (31 eyes) and 15 non-CL patients (20 eyes) who fulfilled the criteria of: 1) >3 years follow-up and 2) Scheimpflug-based corneal imaging...

Does pregnancy cause progression of keratoconus in previously cross-linked corneas?

This is a prospective study involving 24 eyes of 19 patients with stabilised or regressed keratoconus after a successful accelerated cross linking (A-CXL) treatment. Patients were recruited at a routine follow-up visit in the first month of their pregnancy. The...

Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...

Comparison of corneal deformation parameters in keratoconic and normal eyes

This study set out to compare biomechanical properties between normal and keratoconic eyes. It was a retrospective study evaluating 89 eyes (47 normal, 42 keratoconic) and a validation arm of 72 eyes (33 normal, 39 keratoconic) using a high speed...

The impact of collagen crosslinking on keratoplasty numbers in keratoconics

A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...

Outcomes of corneal cross-linking in paediatric patients compared to fellow untreated eyes

This retrospective cohort study evaluated long-term visual, refractive, topographic and safety outcomes of corneal cross-linking (CXL) in patients younger than 18-years-old with keratoconus. The study included all consecutive paediatric patients who underwent epithelium-off CXL treatment for keratoconus at the study...