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Comparison of thrombolysis and conservative management in acute retinal ischaemia
The authors present a retrospective cohort study of individuals presenting with acute, painless, monocular vision loss and diagnosed with acute retinal ischaemia. Reasons for exclusion were iatrogenic aetiology, transient vision loss, missing initial visual acuity data, more than 16 hours...
Retinal ischaemia on OCTA and diabetic retinopathy grade
The authors quite rightly point out that quantification of retinal ischaemia has the potential to serve as a biomarker for diabetic retinopathy disease progression. They set out to investigate the relationship between area of ischaemia on a swept source OCTA...
Anterior segment ischaemia (ASI) risk in 3-muscle surgery
The aim of this study was to calculate the risk of clinically evident ASI following simultaneous 3-rectus muscle surgery and safety profile of the same in a relatively large number of patients from a single tertiary care centre. This was...
Comparison of MRI finding in oculomotor cranial nerve palsies as a result of inflammation and ischaemia
This study aimed to explore the value of asymmetric enhancement of the cavernous sinus on MRI for differential diagnosis between ocular myasthenia gravis, ischemic or inflammatory oculomotor cranial nerve palsies. Three groups were recruited consecutively over a 30-month period and...
Ocular ischaemic syndrome in a rat model
Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...
Does Ozurdex affect perfusion status in vein occlusion?
Ozurdex (intravitreal dexamethasone implant) has been approved by National Institute of Health & Care Excellence (NICE) for treatment of patients with macular oedema associated with vein occlusion. This study looks at the change in peripheral perfusion status in patients with...
Is thrombolytic treatment warranted for central retinal artery occlusion?
Central retinal artery occlusion (CRAO) is a subtype of acute ischaemic stroke which results in severe visual loss. Acute CRAO is equivalent to a brain acute ischaemic stroke (AIS), as the obstruction of the central retinal artery (CRA) causes end-organ...A case of ‘60-day glaucoma’
Neovascular glaucoma (NVG) has been called ‘90-’ or ‘100-day glaucoma’ in the past due to its typical development three months after the onset of central retinal vein occlusion (CRVO). In reality, NVG can occur anywhere between two weeks and two...
Rare presentation of giant cell arteritis in Chinese subjects
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...
Recovery outcomes for ocular cranial nerve palsies
The aim of this study was to report the different causes and recovery patterns for patients with acquired and isolated ocular cranial nerve palsies in a prospective observation study of 80 consecutive patients in a single centre. There were 40...The role of aspirin in the treatment of NAION: Benefits and controversies
Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in individuals over 50 with estimated prevalence of 2–10 per 100,000 people, characterised by sudden, unilateral vision loss due to ischaemic injury to the optic nerve head....
