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Review of bupivacaine use in treatment of strabismus

This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...

RetCam use in differential diagnosis for retinoblastoma

The authors aimed to evaluate RetCam fundus photography and fluorescein angiography (FA) findings in pseudo retinoblastoma. This was a retrospective review of 36 eyes of 28 patients (of which six were female) with 22 bilateral cases. Mean age at presentation...

Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma

The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...

Diagnostic error rates for ROP detection by trainee ophthalmologists

The purpose of this study was to characterise common errors in ROP diagnosis by ophthalmologists-in-training in the USA and Canada. Case acquisition was from a web-based system used for ROP assessment from which 20 cases were selected. Fifty-five trainees from...

Laser speckle contrast imaging (LSCI) enables perfusion monitoring of the anterior segment during strabismus surgery: a study on the horizontal rectus muscles

Forty-four eyes with horizontal strabismus surgery involving medial and / or lateral rectus muscle detachment were recruited. The perfusion in the adjacent paralimbal and iris tissue was monitored with LSCI technique, by using a PeriCam PSI NR System. An infrared...

Diagnosis and management of paediatric keratoconus

This article reviews the current literature on paediatric keratoconus diagnosis and management. Paediatric cases pose challenges as they may not vocalise unilateral changes, difficulty in obtaining reliable imaging, faster rates of progression, difficultly with contact lenses and presumed worse outcomes...

Posterior circulation stroke associated demographics, risk factors and aetiology

The authors present a retrospective case notes review of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted...

Comprehensive review of inherited retinal diseases

The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...

Longitudinal findings in children with neurofibromatosis type 1

This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...