You searched for "therapeutics"

359 results found

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

SPOKE launches Indicative Guidance for contact lens opticians and independent prescribers

The Sector Partnership for Optical Knowledge and Education (SPOKE) has published two new Indicative Guidance documents.

Corneal Transplantation

This relatively small book provides a thorough overview of the history of corneal transplantation, an update on the anatomy and physiology of the cornea with particular reference to the components essential to keratoplasty procedures, also graft preparation and storage. There...

Management of diabetic macular oedema (DMO)

The authors present guidelines on current diagnostic and therapeutic procedures in the management of DMO. Fluorescein angiography (FA) and optical coherence tomography (OCT) are recommended before starting treatment to help diagnose and stage DMO, and can be repeated if there...

IVTA use in Behçet’s disease

This study aimed to evaluate the efficacy and safety of intravitreal triamcinolone acetonide (IVTA) injection (4mg/0.1ml) in controlling posterior segment inflammation in patients with Behçet’s disease. Medical records of consecutive patients diagnosed with Behçet’s who underwent IVTA between July 2005...

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

Results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions

This retrospective, observational multicentre study investigated the anatomic and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes. Data was collected...

Changes in ocular biomarkers in Vogt-Koyanagi-Harada disease after pulse steroid therapy

This retrospective study aimed to evaluate the early and chronological changes in ocular biomarkers in patients of Vogt Koyanagi Harada (VKH) disease who received pulse steroid therapy. It further aimed to identify which biomarkers correlated with the best corrected visual...

Learnings and trends in the management of open-angle and angle-closure glaucoma

To be truly disruptive, newer technologies need to offer a quality of life benefit over medication to a broad population of glaucoma sufferers. Evidence and converging trends in medical and surgical management of glaucoma were explored in counterpoint discussions and...

Birdshot retinochoroiditis

Birdshot retinochoroiditis (BRC) is a chronic, sight-threatening uveitis, most commonly affecting caucasian individuals in their fourth to sixth decades [1]. The disease is associated with HLA-29 and is characterised by progressive inflammation at the level of retina and choroid, with...

Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...