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2549 results found

A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Air or SF6 in DMEK

This retrospective study compared descemet’s membrane endothelial keratoplasty (DMEK) outcomes in 136 consecutive eyes of 68 patients. All patients underwent DMEK for Fuch’s endothelial dystrophy, where consecutive eyes received 100% air bubble during first eye surgery and 20% sulphur hexafluoride...

Myopic choroidal neovascularisation

This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...

Visual recovery following Ex-Press vs. trab

The authors describe a prospective randomised study of 64 POAG subjects with controlled IOPs comparing visual acuity data in patients randomised to either Ex-Press model P50 or trabeculectomy. Visual acuities were recorded at baseline, day one, weeks one and two...

Better outcomes from early repair of Type B blow-out fractures

This paper examines whether early, rather than late, surgical repair results in better motility outcomes for a particular subgroup of orbital floor blowout fractures. The authors divide floor fractures into Types A and B, depending on whether or not the...

A new technique for correction of medial ectropion with a lax medial canthal tendon

This is a prospective study of a new technique for repair of medial ectropion associated with medial canthal tendon (MCT) laxity. The procedure was performed on 79 eyes and involved excision of an ellipse of tissue from below the punctum...

Results of changed treatment for retinoblastoma

Systemic chemotherapy was adopted in Kobe in 1996. In this study the authors analyse the clinical manifestations and results of treatment for patients with retinoblastoma since then. This review is of 43 eyes of 34 patients. Those with follow-up to...

Intravitreal dexamethasone implant for diabetic macular oedema

The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

Timing of vitrectomy for retained lens fragments

The purpose of this study was to compare the results of same setting vitrectomy with delayed vitrectomy for retained lens fragments following cataract surgery. Same setting vitrectomy was defined as the patient not leaving the operating table following cataract surgery....

Outcomes of corneal cross-linking in paediatric patients compared to fellow untreated eyes

This retrospective cohort study evaluated long-term visual, refractive, topographic and safety outcomes of corneal cross-linking (CXL) in patients younger than 18-years-old with keratoconus. The study included all consecutive paediatric patients who underwent epithelium-off CXL treatment for keratoconus at the study...

Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome

A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...